Literature DB >> 2832241

Histological diagnosis of scirrhous carcinoma of the stomach using monoclonal antibody S202.

T Yokota1, T Takahashi, T Yamaguchi, K Sawai, E Otsuji, K Kitamura, T Yamane, Y Fujita.   

Abstract

It is sometimes difficult to identify scirrhous carcinoma cells microscopically, since individually separated malignant cells grow into the fibrous tissue without glandular formation. In this study, we used anti-scirrhous carcinoma monoclonal antibody S202, which reacted strongly with 100% of scirrhous gastric cancer samples, in order to evaluate the precise depth to which cancer cells invaded in the stomach wall. The invasive carcinoma cells could be detected more clearly by immunohistochemical staining with S202 than by histological staining with hematoxylin-eosin. Furthermore, S202 was more useful than anti-CEA (carcinoembryonic antigen) antibody.

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Year:  1988        PMID： 2832241     DOI： 10.1007/BF02918849

Source DB:  PubMed          Journal:  Gastroenterol Jpn        ISSN： 0435-1339


  4 in total

1.  Monoclonal antibodies against human scirrhous carcinoma of the stomach.

Authors:  T Yokota; T Takahashi; T Yamaguchi; K Kitamura; T Masuko; Y Hashimoto
Journal:  Gastroenterol Jpn       Date:  1987-10

2.  Gastrointestinal cancer-associated antigen in immunoperoxidase assay.

Authors:  B F Atkinson; C S Ernst; M Herlyn; Z Steplewski; H F Sears; H Koprowski
Journal:  Cancer Res       Date:  1982-11       Impact factor: 12.701

3.  Carcinoembryonic antigen (CEA) expression and heterogeneity in primary and autologous metastatic gastric tumours demonstrated by a monoclonal antibody.

Authors:  M S Hockey; H J Stokes; H Thompson; C S Woodhouse; F Macdonald; J W Fielding; C H Ford
Journal:  Br J Cancer       Date:  1984-02       Impact factor: 7.640

4.  Gastrointestinal cancer-associated antigen CA 19-9 in histological specimens of pancreatic tumours and pancreatitis.

Authors:  C Haglund; J Lindgren; P J Roberts; S Nordling
Journal:  Br J Cancer       Date:  1986-02       Impact factor: 7.640
  4 in total
  1 in total

1.  Localization of antigen defined by anti-scirrhous gastric carcinoma monoclonal antibody S202 in fixed human cancer tissues.

Authors:  T Yokota; T Takahashi; T Yamaguchi; K Sawai; M Shimotsuma; M Doi; T Masuko; Y Hashimoto
Journal:  Gastroenterol Jpn       Date:  1988-12
  1 in total

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