Literature DB >> 28320957

Rationally designed PPARδ-specific agonists and their therapeutic potential for metabolic syndrome.

Rebecca L Cox1.   

Abstract

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Year:  2017        PMID： 28320957      PMCID： PMC5380081          DOI： 10.1073/pnas.1702084114

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  11 in total

Review 1.  Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association.

Authors:  Richard W Nesto; David Bell; Robert O Bonow; Vivian Fonseca; Scott M Grundy; Edward S Horton; Martin Le Winter; Daniel Porte; Clay F Semenkovich; Sidney Smith; Lawrence H Young; Richard Kahn
Journal:  Diabetes Care       Date:  2004-01       Impact factor: 19.112

2.  Identification of a PPARdelta agonist with partial agonistic activity on PPARgamma.

Authors:  Richard V Connors; Zhulun Wang; Martin Harrison; Alex Zhang; Malgorzata Wanska; Steve Hiscock; Brian Fox; Michael Dore; Marc Labelle; Athena Sudom; Sheree Johnstone; Jinsong Liu; Nigel P C Walker; Anne Chai; Karen Siegler; Yang Li; Peter Coward
Journal:  Bioorg Med Chem Lett       Date:  2009-05-09       Impact factor: 2.823

3.  Prevalence of the metabolic syndrome in the United States, 2003-2012.

Authors:  Maria Aguilar; Taft Bhuket; Sharon Torres; Benny Liu; Robert J Wong
Journal:  JAMA       Date:  2015-05-19       Impact factor: 56.272

4.  Alteration of a single amino acid in peroxisome proliferator-activated receptor-alpha (PPAR alpha) generates a PPAR delta phenotype.

Authors:  I Takada; R T Yu; H E Xu; M H Lambert; V G Montana; S A Kliewer; R M Evans; K Umesono
Journal:  Mol Endocrinol       Date:  2000-05

5.  Structural basis for specific ligation of the peroxisome proliferator-activated receptor δ.

Authors:  Chyuan-Chuan Wu; Thomas J Baiga; Michael Downes; James J La Clair; Annette R Atkins; Stephane B Richard; Weiwei Fan; Theresa A Stockley-Noel; Marianne E Bowman; Joseph P Noel; Ronald M Evans
Journal:  Proc Natl Acad Sci U S A       Date:  2017-03-20       Impact factor: 11.205

Review 6.  Peroxisome proliferator-activated receptor structures: ligand specificity, molecular switch and interactions with regulators.

Authors:  Vincent Zoete; Aurelien Grosdidier; Olivier Michielin
Journal:  Biochim Biophys Acta       Date:  2007-01-18

7.  Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome.

Authors:  Toshiya Tanaka; Joji Yamamoto; Satoshi Iwasaki; Hiroshi Asaba; Hiroki Hamura; Yukio Ikeda; Mitsuhiro Watanabe; Kenta Magoori; Ryoichi X Ioka; Keisuke Tachibana; Yuichiro Watanabe; Yasutoshi Uchiyama; Koichi Sumi; Haruhisa Iguchi; Sadayoshi Ito; Takefumi Doi; Takao Hamakubo; Makoto Naito; Johan Auwerx; Masashi Yanagisawa; Tatsuhiko Kodama; Juro Sakai
Journal:  Proc Natl Acad Sci U S A       Date:  2003-12-15       Impact factor: 11.205

Review 8.  Lipids, lipoproteins, and peroxisome proliferator activated receptor-delta.

Authors:  Dennis L Sprecher
Journal:  Am J Cardiol       Date:  2007-12-03       Impact factor: 2.778

9.  Adaptability and selectivity of human peroxisome proliferator-activated receptor (PPAR) pan agonists revealed from crystal structures.

Authors:  Takuji Oyama; Kenji Toyota; Tsuyoshi Waku; Yuko Hirakawa; Naoko Nagasawa; Jun Ichi Kasuga; Yuichi Hashimoto; Hiroyuki Miyachi; Kosuke Morikawa
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2009-07-10

Review 10.  Update on the use of fibrates: focus on bezafibrate.

Authors:  Ilan Goldenberg; Michal Benderly; Uri Goldbourt
Journal:  Vasc Health Risk Manag       Date:  2008
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  6 in total

Review 1.  PPARδ: A Potential Therapeutic Target for the Treatment of Metabolic Hypertension.

Authors:  Yanli Jiang; Qiang Li; Mengxiao Jia; Zhencheng Yan
Journal:  Int J Hypertens       Date:  2019-04-03       Impact factor: 2.420

2.  Accelerated Barrier Repair in Human Skin Explants Induced with a Plant-Derived PPAR-α Activating Complex via Cooperative Interactions.

Authors:  George Majewski; John Craw; Timothy Falla
Journal:  Clin Cosmet Investig Dermatol       Date:  2021-09-18

Review 3.  The Global Epidemic of the Metabolic Syndrome.

Authors:  Mohammad G Saklayen
Journal:  Curr Hypertens Rep       Date:  2018-02-26       Impact factor: 5.369

Review 4.  Integrating Thyroid Hormone Signaling in Hypothalamic Control of Metabolism: Crosstalk Between Nuclear Receptors.

Authors:  Soumaya Kouidhi; Marie-Stéphanie Clerget-Froidevaux
Journal:  Int J Mol Sci       Date:  2018-07-11       Impact factor: 5.923

Review 5.  The Role of PPAR-δ in Metabolism, Inflammation, and Cancer: Many Characters of a Critical Transcription Factor.

Authors:  Yi Liu; Jennifer K Colby; Xiangsheng Zuo; Jonathan Jaoude; Daoyan Wei; Imad Shureiqi
Journal:  Int J Mol Sci       Date:  2018-10-26       Impact factor: 5.923

6.  Whey Peptides Stimulate Differentiation and Lipid Metabolism in Adipocytes and Ameliorate Lipotoxicity-Induced Insulin Resistance in Muscle Cells.

Authors:  Kenneth D'Souza; Angella Mercer; Hannah Mawhinney; Thomas Pulinilkunnil; Chibuike C Udenigwe; Petra C Kienesberger
Journal:  Nutrients       Date:  2020-02-06       Impact factor: 5.717
  6 in total

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