Literature DB >> 28317005

A cost-effective micromilling platform for rapid prototyping of microdevices.

Daniel P Yen1, Yuta Ando1, Keyue Shen2.   

Abstract

Micromilling has great potential in producing microdevices for lab-on-a-chip and organ-on-a-chip applications, but has remained under-utilized due to the high machinery costs and limited accessibility. In this paper, we assessed the machining capabilities of a low-cost 3-D mill in polycarbonate material, which were showcased by the production of microfluidic devices. The study demonstrates that this particular mill is well suited for the fabrication of multi-scale microdevices with feature sizes from micrometers to centimeters.

Entities:  

Keywords:  Lab-on-a-Chip; Microdevice; Microfluidics; Micromilling; Organ-on-a-Chip; Rapid Prototyping

Year:  2016        PMID: 28317005      PMCID: PMC5356927          DOI: 10.1142/S2339547816200041

Source DB:  PubMed          Journal:  Technology (Singap World Sci)


  10 in total

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Authors:  David J Guckenberger; Theodorus E de Groot; Alwin M D Wan; David J Beebe; Edmond W K Young
Journal:  Lab Chip       Date:  2015-06-07       Impact factor: 6.799

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Authors:  Keil J Regehr; Maribella Domenech; Justin T Koepsel; Kristopher C Carver; Stephanie J Ellison-Zelski; William L Murphy; Linda A Schuler; Elaine T Alarid; David J Beebe
Journal:  Lab Chip       Date:  2009-06-04       Impact factor: 6.799

9.  Gradient generation platforms: new directions for an established microfluidic technology.

Authors:  E Berthier; D J Beebe
Journal:  Lab Chip       Date:  2014-09-07       Impact factor: 6.799

10.  Approaching the in vitro clinical trial: engineering organs on chips.

Authors:  A K Capulli; K Tian; N Mehandru; A Bukhta; S F Choudhury; M Suchyta; K K Parker
Journal:  Lab Chip       Date:  2014-09-07       Impact factor: 6.799

  10 in total
  7 in total

1.  Membrane-bound SCF and VCAM-1 synergistically regulate the morphology of hematopoietic stem cells.

Authors:  Jia Hao; Hao Zhou; Kristen Nemes; Daniel Yen; Winfield Zhao; Charles Bramlett; Bowen Wang; Rong Lu; Keyue Shen
Journal:  J Cell Biol       Date:  2021-08-17       Impact factor: 10.539

2.  Recapitulating Tumor Hypoxia in a Cleanroom-Free, Liquid-Pinning-Based Microfluidic Tumor Model.

Authors:  Jeong Min Oh; Hydari Masuma Begum; Yao Lucia Liu; Yuwei Ren; Keyue Shen
Journal:  ACS Biomater Sci Eng       Date:  2022-06-09

3.  Extended culture and imaging of normal and regenerating adult zebrafish hearts in a fluidic device.

Authors:  Joycelyn K Yip; Michael Harrison; Jessi Villafuerte; G Esteban Fernandez; Andrew P Petersen; Ching-Ling Lien; Megan L McCain
Journal:  Lab Chip       Date:  2019-12-24       Impact factor: 6.799

4.  Establishment of Colorectal Cancer Organoids in Microfluidic-Based System.

Authors:  Diana Pinho; Denis Santos; Ana Vila; Sandra Carvalho
Journal:  Micromachines (Basel)       Date:  2021-04-28       Impact factor: 2.891

5.  Evaluating CAR-T Cell Therapy in a Hypoxic 3D Tumor Model.

Authors:  Yuta Ando; Elizabeth L Siegler; Hoang P Ta; Gunce E Cinay; Hao Zhou; Kimberly A Gorrell; Hannah Au; Bethany M Jarvis; Pin Wang; Keyue Shen
Journal:  Adv Healthc Mater       Date:  2019-02-08       Impact factor: 11.092

6.  A Microdevice Platform Recapitulating Hypoxic Tumor Microenvironments.

Authors:  Yuta Ando; Hoang P Ta; Daniel P Yen; Sang-Sin Lee; Sneha Raola; Keyue Shen
Journal:  Sci Rep       Date:  2017-11-09       Impact factor: 4.996

7.  A Systematic Approach for Developing 3D High-Quality PDMS Microfluidic Chips Based on Micromilling Technology.

Authors:  Amin Javidanbardan; Ana M Azevedo; Virginia Chu; João P Conde
Journal:  Micromachines (Basel)       Date:  2021-12-22       Impact factor: 2.891

  7 in total

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