Literature DB >> 28314839

On the Interpretation of the Hazard Ratio and Communication of Survival Benefit.

Andreas Sashegyi1, David Ferry2.   

Abstract

This brief communication will clarify the difference between a relative hazard and a relative risk. We highlight the importance of this difference, and demonstrate in practical terms that 1 minus the hazard ratio should not be interpreted as a risk reduction in the commonly understood sense of the term. This article aims to provide a better understanding of the type of risk reduction that a hazard ratio implies, thereby clarifying the intent in the communication among practitioners and researchers and establishing an accurate and realistic foundation for communicating with patients. The Oncologist 2017;22:484-486. © AlphaMed Press 2017.

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Year:  2017        PMID: 28314839      PMCID: PMC5388384          DOI: 10.1634/theoncologist.2016-0198

Source DB:  PubMed          Journal:  Oncologist        ISSN: 1083-7159


  2 in total

1.  On the clinical meaningfulness of a treatment's effect on a time-to-event variable.

Authors:  Steven Snapinn; Qi Jiang
Journal:  Stat Med       Date:  2011-04-26       Impact factor: 2.373

2.  Interpreting measures of treatment effect in cancer clinical trials.

Authors:  L Douglas Case; Gretchen Kimmick; Electra D Paskett; Kurt Lohman; Robert Tucker
Journal:  Oncologist       Date:  2002
  2 in total
  10 in total

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Authors:  Pierce D Nunley; Eubulus J Kerr; David A Cavanaugh; Phillip Andrew Utter; Peter G Campbell; Rishi Wadhwa; Kelly A Frank; Kyle E Marshall; Marcus B Stone
Journal:  Int J Spine Surg       Date:  2020-06-30

2.  Adjacent Segment Pathology After Treatment With Cervical Disc Arthroplasty or Anterior Cervical Discectomy and Fusion, Part 2: Clinical Results at 7-Year Follow-Up.

Authors:  Pierce D Nunley; Eubulus J Kerr; David A Cavanaugh; Phillip Andrew Utter; Peter G Campbell; Rishi Wadhwa; Kelly A Frank; Kyle E Marshall; Marcus B Stone
Journal:  Int J Spine Surg       Date:  2020-06-30

3.  Assessing the benefits and harms of direct oral anticoagulants in patients with cancer for the prophylaxis and treatment of venous thromboembolism: a systematic review and meta-analysis.

Authors:  Aakash Desai; Bishal Gyawali
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4.  Lack of access to CDK4/6 inhibitors for premenopausal patients with metastatic breast cancer in Brazil: estimation of the number of premature deaths.

Authors:  Tomás Reinert; Rodrigo Pellegrini; Carlos Henrique Barrios
Journal:  Ecancermedicalscience       Date:  2020-07-30

5.  DriverDBv3: a multi-omics database for cancer driver gene research.

Authors:  Shu-Hsuan Liu; Pei-Chun Shen; Chen-Yang Chen; An-Ni Hsu; Yi-Chun Cho; Yo-Liang Lai; Fang-Hsin Chen; Chia-Yang Li; Shu-Chi Wang; Ming Chen; I-Fang Chung; Wei-Chung Cheng
Journal:  Nucleic Acids Res       Date:  2020-01-08       Impact factor: 16.971

6.  Non-surgical oral hygiene interventions on disease activity of Rheumatoid arthritis patients with periodontitis: A randomized controlled trial.

Authors:  William Buwembo; Ian Guyton Munabi; Mark Kaddumukasa; Haruna Kiryowa; Muhammad Mbabali; Ethel Nankya; William Evan Johnson; Emmy Okello; Nelson K Sewankambo
Journal:  J Dent Res Dent Clin Dent Prospects       Date:  2020

7.  Multi-Approach Bioinformatics Analysis of Curated Omics Data Provides a Gene Expression Panorama for Multiple Cancer Types.

Authors:  Bruno César Feltes; Joice de Faria Poloni; Itamar José Guimarães Nunes; Sara Socorro Faria; Marcio Dorn
Journal:  Front Genet       Date:  2020-11-23       Impact factor: 4.599

8.  The association between plate location and hardware removal following ulna shortening osteotomy: a cohort study.

Authors:  Joris S Teunissen; Sanharib Al Shaer; Brigitte P A van der Heijden; Ruud W Selles; Steven E R Hovius; Oliver T Zöphel
Journal:  J Hand Surg Eur Vol       Date:  2022-04-11

9.  Accelerated Hyperfractionated Radiotherapy versus Conventional Fractionation Radiotherapy for Head and Neck Cancer: A Meta-Analysis of Randomized Controlled Trials.

Authors:  Bo Zhu; Changgui Kou; Wei Bai; Weiying Yu; Lili Zhang; Xiao Yu; Wen Xu; Huanhuan Wang; Ying Xin; Xin Jiang
Journal:  J Oncol       Date:  2019-11-28       Impact factor: 4.375

10.  Long-Term Association of Air Pollution and Hospital Admissions Among Medicare Participants Using a Doubly Robust Additive Model.

Authors:  Mahdieh Danesh Yazdi; Yan Wang; Qian Di; Yaguang Wei; Weeberb J Requia; Liuhua Shi; Matthew Benjamin Sabath; Francesca Dominici; Brent A Coull; John S Evans; Petros Koutrakis; Joel D Schwartz
Journal:  Circulation       Date:  2021-02-22       Impact factor: 29.690

  10 in total

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