Literature DB >> 2831460

Peptide growth factors are multifunctional.

M B Sporn1, A B Roberts.   

Abstract

The actions of many peptide growth factors include both stimulation and inhibition of cell proliferation, as well as effects unrelated to the control of cell growth. One peptide can have both stimulatory and inhibitory activity in a single cell, depending on the context of the other signal molecules present.

Mesh：

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Year:  1988        PMID： 2831460     DOI： 10.1038/332217a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  116 in total

1.  Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis.

Authors:  Y E Chin; M Kitagawa; K Kuida; R A Flavell; X Y Fu
Journal:  Mol Cell Biol       Date:  1997-09       Impact factor: 4.272

2.  Intravitreal growth factors in proliferative diabetic retinopathy: correlation with neovascular activity and glycaemic management.

Authors:  M Boulton; Z Gregor; D McLeod; D Charteris; J Jarvis-Evans; P Moriarty; A Khaliq; D Foreman; D Allamby; B Bardsley
Journal:  Br J Ophthalmol       Date:  1997-03       Impact factor: 4.638

3.  Mitogenic activity for fibroblasts induced by silica and titanium dioxide particles in vitro and in vivo.

Authors:  R K Kumar; R O'Grady; W Li; G M Velan
Journal:  Int J Exp Pathol       Date:  1992-10       Impact factor: 1.925

4.  Adaptive cellular interactions in the immune system: the tunable activation threshold and the significance of subthreshold responses.

Authors:  Z Grossman; W E Paul
Journal:  Proc Natl Acad Sci U S A       Date:  1992-11-01       Impact factor: 11.205

Review 5.  Polypeptide growth factors and the kidney: a developmental perspective.

Authors:  E D Avner
Journal:  Pediatr Nephrol       Date:  1990-07       Impact factor: 3.714

6.  Multiple functions of let-23, a Caenorhabditis elegans receptor tyrosine kinase gene required for vulval induction.

Authors:  R V Aroian; P W Sternberg
Journal:  Genetics       Date:  1991-06       Impact factor: 4.562

Review 7.  TGF-beta: problems and prospects.

Authors:  M B Sporn; A B Roberts
Journal:  Cell Regul       Date:  1990-11

Review 8.  Growth inhibitors: molecular diversity and roles in cell proliferation.

Authors:  K Miyazaki; T Horio
Journal:  In Vitro Cell Dev Biol       Date:  1989-10

Review 9.  A proposed growth regulatory function for the serologically detectable sex-specific antigen H-Ys.

Authors:  B F Heslop; M P Bradley; M A Baird
Journal:  Hum Genet       Date:  1989-01       Impact factor: 4.132

10.  Growth factor expression in aorta of normotensive and hypertensive rats.

Authors:  R Sarzani; P Brecher; A V Chobanian
Journal:  J Clin Invest       Date:  1989-04       Impact factor: 14.808
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