Literature DB >> 28299723

Mold and Human Health: a Reality Check.

Andrea T Borchers1, Christopher Chang1, M Eric Gershwin2.   

Abstract

There are possibly millions of mold species on earth. The vast majority of these mold spores live in harmony with humans, rarely causing disease. The rare species that does cause disease does so by triggering allergies or asthma, or may be involved in hypersensitivity diseases such as allergic bronchopulmonary aspergillosis or allergic fungal sinusitis. Other hypersensitivity diseases include those related to occupational or domiciliary exposures to certain mold species, as in the case of Pigeon Breeder's disease, Farmer's lung, or humidifier fever. The final proven category of fungal diseases is through infection, as in the case of onchomycosis or coccidiomycosis. These diseases can be treated using anti-fungal agents. Molds and fungi can also be particularly important in infections that occur in immunocompromised patients. Systemic candidiasis does not occur unless the individual is immunodeficient. Previous reports of "toxic mold syndrome" or "toxic black mold" have been shown to be no more than media hype and mass hysteria, partly stemming from the misinterpreted concept of the "sick building syndrome." There is no scientific evidence that exposure to visible black mold in apartments and buildings can lead to the vague and subjective symptoms of memory loss, inability to focus, fatigue, and headaches that were reported by people who erroneously believed that they were suffering from "mycotoxicosis." Similarly, a causal relationship between cases of infant pulmonary hemorrhage and exposure to "black mold" has never been proven. Finally, there is no evidence of a link between autoimmune disease and mold exposure.

Entities:  

Keywords:  Allergic bronchopulmonary aspergillosis; Allergic fungal sinusitis; Allergic rhinitis; Asthma; Fungi; Hypersensitivity pneumonitis; Mycotoxicosis; Mycotoxins; Sick building syndrome

Mesh:

Substances:

Year:  2017        PMID: 28299723     DOI: 10.1007/s12016-017-8601-z

Source DB:  PubMed          Journal:  Clin Rev Allergy Immunol        ISSN: 1080-0549            Impact factor:   8.667


  178 in total

1.  Relationships between mite allergen levels, mold concentrations, and sick building syndrome symptoms in newly built dwellings in Japan.

Authors:  Y Saijo; A Kanazawa; A Araki; K Morimoto; K Nakayama; T Takigawa; M Tanaka; E Shibata; T Yoshimura; H Chikara; R Kishi
Journal:  Indoor Air       Date:  2010-12-28       Impact factor: 5.770

2.  Microbial volatile organic compounds in the air of moldy and mold-free indoor environments.

Authors:  H Schleibinger; D Laussmann; C-G Bornehag; D Eis; H Rueden
Journal:  Indoor Air       Date:  2008-04       Impact factor: 5.770

3.  Multiple comparisons of organic, microbial, and fine particulate pollutants in typical indoor environments: diurnal and seasonal variations.

Authors:  Sibel Mentese; Abbas Yousefi Rad; Münevver Arisoy; Gülen Güllü
Journal:  J Air Waste Manag Assoc       Date:  2012-12       Impact factor: 2.235

4.  Dampness, bacterial and fungal components in dust in primary schools and respiratory health in schoolchildren across Europe.

Authors:  José Jacobs; Alicia Borràs-Santos; Esmeralda Krop; Martin Täubel; Hanna Leppänen; Ulla Haverinen-Shaughnessy; Juha Pekkanen; Anne Hyvärinen; Gert Doekes; Jan-Paul Zock; Dick Heederik
Journal:  Occup Environ Med       Date:  2014-07-17       Impact factor: 4.402

Review 5.  Immunity, tolerance and autoimmunity in the liver: A comprehensive review.

Authors:  Derek G Doherty
Journal:  J Autoimmun       Date:  2015-09-07       Impact factor: 7.094

6.  How does airway exposure of aflatoxin B1 affect serum albumin adduct concentrations? Evidence based on epidemiological study and animal experimentation.

Authors:  Xianwei Mo; Hao Lai; Yang Yang; Jun Xiao; Ke He; Chao Liu; Jiansi Chen; Yuan Lin
Journal:  J Toxicol Sci       Date:  2014-08       Impact factor: 2.196

Review 7.  Induction of regulatory T cells: A role for probiotics and prebiotics to suppress autoimmunity.

Authors:  Mitesh Dwivedi; Prasant Kumar; Naresh C Laddha; E Helen Kemp
Journal:  Autoimmun Rev       Date:  2016-01-07       Impact factor: 9.754

Review 8.  Epigenetic Variability of CD4+CD25+ Tregs Contributes to the Pathogenesis of Autoimmune Diseases.

Authors:  Ye Shu; Qinghua Hu; Hai Long; Christopher Chang; Qianjin Lu; Rong Xiao
Journal:  Clin Rev Allergy Immunol       Date:  2017-04       Impact factor: 8.667

9.  Trichothecene mycotoxins in aerosolized conidia of Stachybotrys atra.

Authors:  W G Sorenson; D G Frazer; B B Jarvis; J Simpson; V A Robinson
Journal:  Appl Environ Microbiol       Date:  1987-06       Impact factor: 4.792

10.  Allergy and respiratory health effects of dampness and dampness-related agents in schools and homes: a cross-sectional study in Danish pupils.

Authors:  G J Holst; A Høst; G Doekes; H W Meyer; A M Madsen; K B Plesner; T Sigsgaard
Journal:  Indoor Air       Date:  2016-01-05       Impact factor: 5.770

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  9 in total

Review 1.  Indoor Environmental Interventions for Furry Pet Allergens, Pest Allergens, and Mold: Looking to the Future.

Authors:  Sharon K Ahluwalia; Elizabeth C Matsui
Journal:  J Allergy Clin Immunol Pract       Date:  2018 Jan - Feb

Review 2.  The Myth of Mycotoxins and Mold Injury.

Authors:  Christopher Chang; M Eric Gershwin
Journal:  Clin Rev Allergy Immunol       Date:  2019-12       Impact factor: 8.667

Review 3.  Bedroom Allergen Exposure Beyond House Dust Mites.

Authors:  Paivi M Salo; Richard D Cohn; Darryl C Zeldin
Journal:  Curr Allergy Asthma Rep       Date:  2018-08-20       Impact factor: 4.806

4.  Chloroanisoles and Chlorophenols Explain Mold Odor but Their Impact on the Swedish Population Is Attributed to Dampness and Mold.

Authors:  Johnny C Lorentzen; Stephanie A Juran; Lena Ernstgård; Mats J Olsson; Gunnar Johanson
Journal:  Int J Environ Res Public Health       Date:  2020-02-03       Impact factor: 3.390

5.  The bacterial community of childcare centers: potential implications for microbial dispersal and child exposure.

Authors:  D E Beasley; A A Madden; M Monsur; J Hu; R R Dunn
Journal:  Environ Microbiome       Date:  2022-03-04

6.  Is in vitro cytokine release a suitable marker to improve the diagnosis of suspected mold-related respiratory symptoms? A proof-of-concept study.

Authors:  Verena Liebers; Sabine Kespohl; Gerda Borowitzki; Heike Stubel; Monika Raulf
Journal:  Allergol Select       Date:  2022-03-29

Review 7.  Recent Advances in the Allergic Cross-Reactivity between Fungi and Foods.

Authors:  Haiyan Xing; Jianyong Wang; Yuemei Sun; Hongtian Wang
Journal:  J Immunol Res       Date:  2022-10-07       Impact factor: 4.493

8.  Turkish Guideline for Diagnosis and Treatment of Allergic Rhinitis (ART).

Authors:  Mustafa Cenk Ecevit; Müge Özcan; İlknur Haberal Can; Emel Çadallı Tatar; Serdar Özer; Erkan Esen; Doğan Atan; Sercan Göde; Çağdaş Elsürer; Aylin Eryılmaz; Berna Uslu Coşkun; Zahide Mine Yazıcı; Mehmet Emre Dinç; Fatih Özdoğan; Kıvanç Günhan; Nagihan Bilal; Arzu Yasemin Korkut; Fikret Kasapoğlu; Bilge Türk; Ela Araz Server; Özlem Önerci Çelebi; Tuğçe Şimşek; Rauf Oğuzhan Kum; Mustafa Kemal Adalı; Erdem Eren; Nesibe Gül Yüksel Aslıer; Tuba Bayındır; Aslı Çakır Çetin; Ayşe Enise Göker; Işıl Adadan Güvenç; Sabri Köseoğlu; Gül Soylu Özler; Ethem Şahin; Aslı Şahin Yılmaz; Ceren Güne; Gökçe Aksoy Yıldırım; Bülent Öca; Mehmet Durmuşoğlu; Yunus Kantekin; Süay Özmen; Gözde Orhan Kubat; Serap Köybaşı Şanal; Emine Elif Altuntaş; Adin Selçuk; Haşmet Yazıcı; Deniz Baklacı; Atılay Yaylacı; Deniz Hancı; Sedat Doğan; Vural Fidan; Kemal Uygur; Nesil Keleş; Cemal Cingi; Bülent Topuz; Salih Çanakçıoğlu; Metin Önerci
Journal:  Turk Arch Otorhinolaryngol       Date:  2021-05

Review 9.  The allergenic activity and clinical impact of individual IgE-antibody binding molecules from indoor allergen sources.

Authors:  Luis Caraballo; Rudolf Valenta; Leonardo Puerta; Anna Pomés; Josefina Zakzuk; Enrique Fernandez-Caldas; Nathalie Acevedo; Mario Sanchez-Borges; Ignacio Ansotegui; Luo Zhang; Marianne van Hage; Eva Fernández; Luisa Arruda; Susanne Vrtala; Mirela Curin; Hans Gronlund; Antonina Karsonova; Jonathan Kilimajer; Ksenja Riabova; Daria Trifonova; Alexander Karaulov
Journal:  World Allergy Organ J       Date:  2020-04-29       Impact factor: 4.084

  9 in total

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