Literature DB >> 28295340

Directional excitatory input to direction-selective ganglion cells in the rabbit retina.

Kumiko A Percival1, Sowmya Venkataramani1, Robert G Smith2, W Rowland Taylor1.   

Abstract

Directional responses in retinal ganglion cells are generated in large part by direction-selective release of γ-aminobutyric acid from starburst amacrine cells onto direction-selective ganglion cells (DSGCs). The excitatory inputs to DSGCs are also widely reported to be direction-selective, however, recent evidence suggests that glutamate release from bipolar cells is not directional, and directional excitation seen in patch-clamp analyses may be an artifact resulting from incomplete voltage control. Here, we test this voltage-clamp-artifact hypothesis in recordings from 62 ON-OFF DSGCs in the rabbit retina. The strength of the directional excitatory signal varies considerably across the sample of cells, but is not correlated with the strength of directional inhibition, as required for a voltage-clamp artifact. These results implicate additional mechanisms in generating directional excitatory inputs to DSGCs.
© 2017 Wiley Periodicals, Inc.

Entities:  

Keywords:  RRID:SCR_000325; amacrine cells; direction selective; excitation; inhibition; rabbit; retinal ganglion cell; synaptic transmission; voltage clamp

Mesh:

Year:  2017        PMID: 28295340      PMCID: PMC5599367          DOI: 10.1002/cne.24207

Source DB:  PubMed          Journal:  J Comp Neurol        ISSN: 0021-9967            Impact factor:   3.215


  44 in total

1.  The role of NMDA channels in rabbit retinal directional selectivity.

Authors:  D S Tjepkes; F R Amthor
Journal:  Vis Neurosci       Date:  2000 Mar-Apr       Impact factor: 3.241

2.  Conditional Knock-Out of Vesicular GABA Transporter Gene from Starburst Amacrine Cells Reveals the Contributions of Multiple Synaptic Mechanisms Underlying Direction Selectivity in the Retina.

Authors:  Zhe Pei; Qiang Chen; David Koren; Benno Giammarinaro; Hector Acaron Ledesma; Wei Wei
Journal:  J Neurosci       Date:  2015-09-23       Impact factor: 6.167

3.  Directional selectivity is formed at multiple levels by laterally offset inhibition in the rabbit retina.

Authors:  Shelley I Fried; Thomas A Münch; Frank S Werblin
Journal:  Neuron       Date:  2005-04-07       Impact factor: 17.173

4.  Symmetric interactions within a homogeneous starburst cell network can lead to robust asymmetries in dendrites of starburst amacrine cells.

Authors:  Thomas A Münch; Frank S Werblin
Journal:  J Neurophysiol       Date:  2006-04-05       Impact factor: 2.714

5.  The synaptic mechanism of direction selectivity in distal processes of starburst amacrine cells.

Authors:  Seunghoon Lee; Z Jimmy Zhou
Journal:  Neuron       Date:  2006-09-21       Impact factor: 17.173

6.  Visibility of synaptically induced conductance changes: theory and simulations of anatomically characterized cortical pyramidal cells.

Authors:  C Koch; R Douglas; U Wehmeier
Journal:  J Neurosci       Date:  1990-06       Impact factor: 6.167

7.  Excitatory synaptic inputs to mouse on-off direction-selective retinal ganglion cells lack direction tuning.

Authors:  Silvia J H Park; In-Jung Kim; Loren L Looger; Jonathan B Demb; Bart G Borghuis
Journal:  J Neurosci       Date:  2014-03-12       Impact factor: 6.167

8.  Voltage- and space-clamp errors associated with the measurement of electrotonically remote synaptic events.

Authors:  N Spruston; D B Jaffe; S H Williams; D Johnston
Journal:  J Neurophysiol       Date:  1993-08       Impact factor: 2.714

9.  Species-specific wiring for direction selectivity in the mammalian retina.

Authors:  Huayu Ding; Robert G Smith; Alon Poleg-Polsky; Jeffrey S Diamond; Kevin L Briggman
Journal:  Nature       Date:  2016-06-22       Impact factor: 49.962

10.  Stimulus-dependent recruitment of lateral inhibition underlies retinal direction selectivity.

Authors:  Qiang Chen; Zhe Pei; David Koren; Wei Wei
Journal:  Elife       Date:  2016-12-08       Impact factor: 8.140

View more
  7 in total

1.  Cholinergic excitation complements glutamate in coding visual information in retinal ganglion cells.

Authors:  Santhosh Sethuramanujam; Gautam B Awatramani; Malcolm M Slaughter
Journal:  J Physiol       Date:  2018-06-21       Impact factor: 5.182

Review 2.  Stimulus-dependent engagement of neural mechanisms for reliable motion detection in the mouse retina.

Authors:  Qiang Chen; Wei Wei
Journal:  J Neurophysiol       Date:  2018-06-13       Impact factor: 2.714

3.  Molecular Fingerprinting of On-Off Direction-Selective Retinal Ganglion Cells Across Species and Relevance to Primate Visual Circuits.

Authors:  Onkar S Dhande; Benjamin K Stafford; Katrin Franke; Rana El-Danaf; Kumiko A Percival; Ann H Phan; Peichao Li; Bryan J Hansen; Phong L Nguyen; Philipp Berens; W Rowland Taylor; Edward Callaway; Thomas Euler; Andrew D Huberman
Journal:  J Neurosci       Date:  2018-10-30       Impact factor: 6.167

4.  Spatiotemporally Asymmetric Excitation Supports Mammalian Retinal Motion Sensitivity.

Authors:  Akihiro Matsumoto; Kevin L Briggman; Keisuke Yonehara
Journal:  Curr Biol       Date:  2019-09-26       Impact factor: 10.834

5.  Preserving inhibition with a disinhibitory microcircuit in the retina.

Authors:  Qiang Chen; Robert G Smith; Xiaolin Huang; Wei Wei
Journal:  Elife       Date:  2020-12-03       Impact factor: 8.140

6.  Receptoral Mechanisms for Fast Cholinergic Transmission in Direction-Selective Retinal Circuitry.

Authors:  Joseph Pottackal; Joshua H Singer; Jonathan B Demb
Journal:  Front Cell Neurosci       Date:  2020-11-26       Impact factor: 5.505

7.  Antagonistic Center-Surround Mechanisms for Direction Selectivity in the Retina.

Authors:  Lea Ankri; Elishai Ezra-Tsur; Shir R Maimon; Nathali Kaushansky; Michal Rivlin-Etzion
Journal:  Cell Rep       Date:  2020-05-05       Impact factor: 9.423

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.