Literature DB >> 2829430

Gene transfer into hematopoietic progenitor cells mediated by an adeno-associated virus vector.

D LaFace1, P Hermonat, E Wakeland, A Peck.   

Abstract

We describe here the transduction of murine hematopoietic progenitor cells with the dominant selectable neomycin drug-resistance (Neo) gene using a recombinant adeno-associated virus (AAV) vector. Successful transformation of progenitor cells to drug resistance was determined to be approximately 1.5% by colony formation in the presence of geneticin sulfate (G-418). The value of AAV as an alternative to the retrovirus vector systems is discussed.

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Year:  1988        PMID： 2829430     DOI： 10.1016/0042-6822(88)90491-6

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


  13 in total

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Authors:  K I Berns
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3.  Dynamic DNA methylation and histone modifications contribute to lentiviral transgene silencing in murine embryonic carcinoma cells.

Authors:  Jin He; Qing Yang; Lung-Ji Chang
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4.  DNA double-strand break repair functions defend against parvovirus infection.

Authors:  T J Tauer; M H Schneiderman; J K Vishwanatha; S L Rhode
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5.  Adeno-Associated Virus and Hematopoietic Stem Cells: The Potential of Adeno-Associated Virus Hematopoietic Stem Cells in Genetic Medicines.

Authors:  Saswati Chatterjee; Venkatesh Sivanandam; Kamehameha Kai-Min Wong
Journal:  Hum Gene Ther       Date:  2020-05       Impact factor: 5.695

6.  Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis.

Authors:  K J Fisher; G P Gao; M D Weitzman; R DeMatteo; J F Burda; J M Wilson
Journal:  J Virol       Date:  1996-01       Impact factor: 5.103

7.  Efficient gene transfer into nondividing cells by adeno-associated virus-based vectors.

Authors:  G Podsakoff; K K Wong; S Chatterjee
Journal:  J Virol       Date:  1994-09       Impact factor: 5.103

8.  Regulated high level expression of a human gamma-globin gene introduced into erythroid cells by an adeno-associated virus vector.

Authors:  C E Walsh; J M Liu; X Xiao; N S Young; A W Nienhuis; R J Samulski
Journal:  Proc Natl Acad Sci U S A       Date:  1992-08-01       Impact factor: 11.205

Review 9.  Adeno-associated virus (AAV) vectors: will they work?

Authors:  N Muzyczka
Journal:  J Clin Invest       Date:  1994-10       Impact factor: 14.808

10.  Phenotypic correction of Fanconi anemia in human hematopoietic cells with a recombinant adeno-associated virus vector.

Authors:  C E Walsh; A W Nienhuis; R J Samulski; M G Brown; J L Miller; N S Young; J M Liu
Journal:  J Clin Invest       Date:  1994-10       Impact factor: 14.808
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