Literature DB >> 28292437

Nerve Dependence: From Regeneration to Cancer.

Benoni Boilly1, Sam Faulkner2, Phillip Jobling2, Hubert Hondermarck3.   

Abstract

Nerve dependence has long been described in animal regeneration, where the outgrowth of axons is necessary to the reconstitution of lost body parts and tissue remodeling in various species. Recent discoveries have demonstrated that denervation can suppress tumor growth and metastasis, pointing to nerve dependence in cancer. Regeneration and cancer share similarities in regard to the stimulatory role of nerves, and there are indications that the stem cell compartment is a preferred target of innervation. Thus, the neurobiology of cancer is an emerging discipline that opens new perspectives in oncology.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Schwann cells; cancer; nerve dependence; nerve infiltration; neurotrophic growth factors; regeneration; tumor microenvironment

Mesh:

Substances:

Year:  2017        PMID: 28292437     DOI: 10.1016/j.ccell.2017.02.005

Source DB:  PubMed          Journal:  Cancer Cell        ISSN: 1535-6108            Impact factor:   31.743


  56 in total

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Journal:  Ann Transl Med       Date:  2018-03

3.  Rethinking carcinogenesis: The detached pericyte hypothesis.

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Journal:  Nat Rev Cancer       Date:  2020-01-23       Impact factor: 60.716

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Journal:  Ann Surg Oncol       Date:  2020-06-09       Impact factor: 5.344

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Authors:  Salvador Rojas; Néstor J Oviedo
Journal:  DNA Repair (Amst)       Date:  2021-04-20

Review 8.  Many Voices in a Choir: Tumor-Induced Neurogenesis and Neuronal Driven Alternative Splicing Sound Like Suspects in Tumor Growth and Dissemination.

Authors:  Zodwa Dlamini; Kgomotso Mathabe; Llewellyn Padayachy; Rahaba Marima; George Evangelou; Konstantinos N Syrigos; Arianna Bianchi; Georgios Lolas; Rodney Hull
Journal:  Cancers (Basel)       Date:  2021-04-29       Impact factor: 6.639

Review 9.  Alternative Animal Models of Aging Research.

Authors:  Susanne Holtze; Ekaterina Gorshkova; Stan Braude; Alessandro Cellerino; Philip Dammann; Thomas B Hildebrandt; Andreas Hoeflich; Steve Hoffmann; Philipp Koch; Eva Terzibasi Tozzini; Maxim Skulachev; Vladimir P Skulachev; Arne Sahm
Journal:  Front Mol Biosci       Date:  2021-05-17

10.  The Stage-Specific Plasticity of Descending Modulatory Controls in a Rodent Model of Cancer-Induced Bone Pain.

Authors:  Mateusz Wojciech Kucharczyk; Diane Derrien; Anthony Henry Dickenson; Kirsty Bannister
Journal:  Cancers (Basel)       Date:  2020-11-06       Impact factor: 6.639

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