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Literature DB >> 2829212

Isolation and expression of rat 1,25-dihydroxyvitamin D3 receptor cDNA.

Abstract

The cDNA for the 1,25-dihydroxyvitamin D3 receptor has been isolated by screening a rat kidney lambda gt11 expression library with a mixture of three previously identified anti-receptor monoclonal antibodies. Protein produced from this cDNA reacts with each of the three monoclonal antibodies but does not react with an antibody specific for the porcine receptor or an irrelevant antibody. In addition, the expressed protein specifically binds 1,25-dihydroxyvitamin D3 but does not bind estradiol, progesterone, testosterone, cortisol, or aldosterone. The nucleotide sequence for this cDNA has been determined and used to deduce the amino acid sequence of the protein. This amino acid sequence contains a region that matches perfectly the partial amino acid sequence determined for the receptor isolated from porcine intestine. This amino acid sequence also closely matches the reported amino acid sequence of the putative DNA-binding finger of the avian 1,25-dihydroxyvitamin D3 receptor.

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Year: 1988 PMID： 2829212 PMCID： PMC279689 DOI： 10.1073/pnas.85.4.1005

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

13 in total

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Authors: M C Dame; E A Pierce; J M Prahl; C E Hayes; H F DeLuca
Journal: Biochemistry Date: 1986-08-12 Impact factor: 3.162

2. A new method for sequencing DNA.

Authors: A M Maxam; W Gilbert
Journal: Proc Natl Acad Sci U S A Date: 1977-02 Impact factor: 11.205

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Authors: J W Pike
Journal: J Biol Chem Date: 1984-01-25 Impact factor: 5.157

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Authors: R A Young; R W Davis
Journal: Proc Natl Acad Sci U S A Date: 1983-03 Impact factor: 11.205

5. A cellular defect in hereditary vitamin-D-dependent rickets type II: defective nuclear uptake of 1,25-dihydroxyvitamin D in cultured skin fibroblasts.

Authors: C Eil; U A Liberman; J F Rosen; S J Marx
Journal: N Engl J Med Date: 1981-06-25 Impact factor: 91.245

6. Molecular cloning of complementary DNA encoding the avian receptor for vitamin D.

Authors: D P McDonnell; D J Mangelsdorf; J W Pike; M R Haussler; B W O'Malley
Journal: Science Date: 1987-03-06 Impact factor: 47.728

7. Vitamin D3--resistant fibroblasts have immunoassayable 1,25-dihydroxyvitamin D3 receptors.

Authors: J W Pike; S Dokoh; M R Haussler; U A Liberman; S J Marx; C Eil
Journal: Science Date: 1984-05-25 Impact factor: 47.728

8. Development of hybridomas secreting monoclonal antibodies to the chicken intestinal 1 alpha,25-dihydroxyvitamin D3 receptor.

Authors: J W Pike; C A Donaldson; S L Marion; M R Haussler
Journal: Proc Natl Acad Sci U S A Date: 1982-12 Impact factor: 11.205

9. A deoxyribonucleic acid polymerase from Micrococcus luteus (Micrococcus lysodeikticus) isolated on deoxyribonucleic acid-cellulose.

Authors: R M Litman
Journal: J Biol Chem Date: 1968-12-10 Impact factor: 5.157

10. Direct chemical synthesis of 1 alpha,25-dihydroxy[26,27-3H]vitamin D3 with high specific activity: its use in receptor studies.

Authors: J L Napoli; W S Mellon; M A Fivizzani; H K Schnoes; H F DeLuca
Journal: Biochemistry Date: 1980-05-27 Impact factor: 3.162

22 in total

Review 1. Evolution and function of the NR1I nuclear hormone receptor subfamily (VDR, PXR, and CAR) with respect to metabolism of xenobiotics and endogenous compounds.

Authors: E J Reschly; Matthew D Krasowski
Journal: Curr Drug Metab Date: 2006-05 Impact factor: 3.731

2. Overproduction of rat 1,25-dihydroxyvitamin D3 receptor in insect cells using the baculovirus expression system.

Authors: T K Ross; J M Prahl; H F DeLuca
Journal: Proc Natl Acad Sci U S A Date: 1991-08-01 Impact factor: 11.205

Review 3. Biology and Mechanisms of Action of the Vitamin D Hormone.

Authors: J Wesley Pike; Sylvia Christakos
Journal: Endocrinol Metab Clin North Am Date: 2017-09-29 Impact factor: 4.741

4. Cloning and characterization of the mouse vitamin D receptor promoter.

Authors: F Jehan; H F DeLuca
Journal: Proc Natl Acad Sci U S A Date: 1997-09-16 Impact factor: 11.205

5. Structure and regulation of the rat 1,25-dihydroxyvitamin D3 receptor.

Authors: J K Burmester; R J Wiese; N Maeda; H F DeLuca
Journal: Proc Natl Acad Sci U S A Date: 1988-12 Impact factor: 11.205

6. Partial amino acid sequence of porcine 1,25-dihydroxyvitamin D3 receptor isolated by immunoaffinity chromatography.

Authors: T A Brown; J M Prahl; H F DeLuca
Journal: Proc Natl Acad Sci U S A Date: 1988-04 Impact factor: 11.205

Review 7. Vitamin D, disease and therapeutic opportunities.

Authors: Lori A Plum; Hector F DeLuca
Journal: Nat Rev Drug Discov Date: 2010-12 Impact factor: 84.694

8. An ochre mutation in the vitamin D receptor gene causes hereditary 1,25-dihydroxyvitamin D3-resistant rickets in three families.

Authors: H H Ritchie; M R Hughes; E T Thompson; P J Malloy; Z Hochberg; D Feldman; J W Pike; B W O'Malley
Journal: Proc Natl Acad Sci U S A Date: 1989-12 Impact factor: 11.205

Review 9. Regulation of gene expression by 1,25-dihydroxyvitamin D3 in bone cells: exploiting new approaches and defining new mechanisms.

Authors: J Wesley Pike; Seong Min Lee; Mark B Meyer
Journal: Bonekey Rep Date: 2014-01-08

10. Vitamin D receptor contains multiple dimerization interfaces that are functionally different.

Authors: J Nishikawa; M Kitaura; M Imagawa; T Nishihara
Journal: Nucleic Acids Res Date: 1995-02-25 Impact factor: 16.971