Literature DB >> 28291272

Automated glycan assembly of branched β-(1,3)-glucans to identify antibody epitopes.

M W Weishaupt1, H S Hahm1, A Geissner1, P H Seeberger1.   

Abstract

β-(1,3)-Glucans exhibit immunomodulatory and anti-tumor effects. Since the isolation of pure β-(1,3)-glucan oligosaccharides from natural sources is complicated, especially when certain branching patterns are desired, chemical synthesis is frequently the only means of accessing these molecules. We report the iterative automated glycan assembly (AGA) of conjugation-ready linear and branched β-(1,3)-glucan oligosaccharides.

Entities:  

Year:  2017        PMID： 28291272     DOI： 10.1039/c7cc00520b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

1.  Improving vaccines against Streptococcus pneumoniae using synthetic glycans.

Authors:  Paulina Kaplonek; Naeem Khan; Katrin Reppe; Benjamin Schumann; Madhu Emmadi; Marilda P Lisboa; Fei-Fei Xu; Adam D J Calow; Sharavathi G Parameswarappa; Martin Witzenrath; Claney L Pereira; Peter H Seeberger
Journal:  Proc Natl Acad Sci U S A       Date:  2018-12-07       Impact factor: 11.205

2.  Creation of Straight-Chain Cationic Polysaccharide-Based Bile Salt Sequestrants Made from Euglenoid β-1,3-Glucan as Potential Antidiabetic Agents.

Authors:  Motonari Shibakami; Kazuhiko Shibata; Akira Akashi; Nobuteru Onaka; Jun Takezaki; Gen Tsubouchi; Hiroaki Yoshikawa
Journal:  Pharm Res       Date:  2018-12-06       Impact factor: 4.200

Review 3.  The Road to Structurally Defined β-Glucans.

Authors:  Patrick Ross; Mark P Farrell
Journal:  Chem Rec       Date:  2021-05-19       Impact factor: 6.935

4.  Traceless Photolabile Linker Expedites the Chemical Synthesis of Complex Oligosaccharides by Automated Glycan Assembly.

Authors:  Kim Le Mai Hoang; Alonso Pardo-Vargas; Yuntao Zhu; Yang Yu; Mirco Loria; Martina Delbianco; Peter H Seeberger
Journal:  J Am Chem Soc       Date:  2019-05-24       Impact factor: 15.419

5.  Photo-cleavable purification/protection handle assisted synthesis of giant modified proteins with tandem repeats.

Authors:  Xueyi Liu; Jiazhi Liu; Zhichao Wu; Liangbiao Chen; Siyao Wang; Ping Wang
Journal:  Chem Sci       Date:  2019-08-12       Impact factor: 9.825

Review 6.  Leloir Glycosyltransferases in Applied Biocatalysis: A Multidisciplinary Approach.

Authors:  Luuk Mestrom; Marta Przypis; Daria Kowalczykiewicz; André Pollender; Antje Kumpf; Stefan R Marsden; Isabel Bento; Andrzej B Jarzębski; Katarzyna Szymańska; Arkadiusz Chruściel; Dirk Tischler; Rob Schoevaart; Ulf Hanefeld; Peter-Leon Hagedoorn
Journal:  Int J Mol Sci       Date:  2019-10-23       Impact factor: 5.923

7.  Unraveling the sugar code: the role of microbial extracellular glycans in plant-microbe interactions.

Authors:  Alan Wanke; Milena Malisic; Stephan Wawra; Alga Zuccaro
Journal:  J Exp Bot       Date:  2021-01-20       Impact factor: 6.992

8.  Noncovalent microarrays from synthetic amino-terminating glycans: Implications in expanding glycan microarray diversity and platform comparison.

Authors:  Chunxia Li; Angelina S Palma; Pengtao Zhang; Yibing Zhang; Chao Gao; Lisete M Silva; Zhen Li; Filipa Trovão; Markus Weishaupt; Peter H Seeberger; Leonid M Likhosherstov; Vladimir Piskarev; Jin Yu; Ulrika Westerlind; Wengang Chai
Journal:  Glycobiology       Date:  2021-09-09       Impact factor: 4.313
  8 in total

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