Literature DB >> 2828968

New delta-receptor antagonists.

C W Thornber1, J S Shaw, L Miller, C F Hayward, J S Morley, D Timms, A Wilkinson.   

Abstract

A new delta-selective opiate antagonist has been synthesised in which the two glycine residues of diallyl leucine enkephalin have been replaced by 4-aminobenzoic acid. The compound has a different conformation to that of ICI 174,864 (N,N-diallyl-Tyr-Aib-Aib-Phe-Leu).

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Year:  1986        PMID: 2828968

Source DB:  PubMed          Journal:  NIDA Res Monogr        ISSN: 1046-9516


  1 in total

Review 1.  Emerging approaches in the molecular design of receptor-selective peptide ligands: conformational, topographical and dynamic considerations.

Authors:  V J Hruby; F al-Obeidi; W Kazmierski
Journal:  Biochem J       Date:  1990-06-01       Impact factor: 3.857

  1 in total

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