Literature DB >> 2536849

Characterization of membrane antigens on human cytomegalovirus-infected fibroblasts recognized by human antibodies.

L H van der Voort1, L F de Leij, T H The.   

Abstract

The antigens on the surface of human cytomegalovirus (HCMV)-infected fibroblasts which are recognized by human HCMV antibody-positive sera were characterized. Three HCMV-induced polypeptides, with apparent molecular masses of 53 to 63, 94, and 94 to 120 kilodaltons, were precipitated from 125I-surface-labeled cell extracts with different sera obtained from healthy individuals. Renal transplant recipients who were suffering from active HCMV infections recognized the same set of antigens. By the use of monoclonal antibodies, these antigens were identified as polypeptides belonging to the gcI and gcIII families of HCMV glycoproteins.

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Year:  1989        PMID： 2536849      PMCID： PMC247857     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  16 in total

1.  Identification and characterization of three distinct families of glycoprotein complexes in the envelopes of human cytomegalovirus.

Authors:  D R Gretch; B Kari; L Rasmussen; R C Gehrz; M F Stinski
Journal:  J Virol       Date:  1988-03       Impact factor: 5.103

2.  Human immune responses to major human cytomegalovirus glycoprotein complexes.

Authors:  Y N Liu; B Kari; R C Gehrz
Journal:  J Virol       Date:  1988-03       Impact factor: 5.103

3.  Immune interactions with cells infected with herpes simplex virus: antibodies to radioiodinated surface antigens.

Authors:  J C Glorioso; J W Smith
Journal:  J Immunol       Date:  1977-01       Impact factor: 5.422

4.  Structural components of human cytomegalovirus: in situ localization of the major glycoprotein.

Authors:  M P Landini; B Severi; L Badiali; E Gonczol; G Mirolo
Journal:  Intervirology       Date:  1987       Impact factor: 1.763

5.  Antibodies against membrane antigens of cytomegalovirus infected cells in sera of patients with a cytomegalovirus infection.

Authors:  T H The; M M Langenhuysen
Journal:  Clin Exp Immunol       Date:  1972-08       Impact factor: 4.330

6.  Human fibroblast-conditioned medium contains a 100K dalton glucose-regulated cell surface protein.

Authors:  P J McCormick; B J Keys; C Pucci; A J Millis
Journal:  Cell       Date:  1979-09       Impact factor: 41.582

7.  Killing of human cytomegalovirus-infected fibroblasts by antiviral antibody and complement.

Authors:  J M Middeldorp; J Jongsma; T H The
Journal:  J Infect Dis       Date:  1986-01       Impact factor: 5.226

8.  Viral polypeptides detected by a complement-dependent neutralizing murine monoclonal antibody to human cytomegalovirus.

Authors:  L Rasmussen; J Mullenax; R Nelson; T C Merigan
Journal:  J Virol       Date:  1985-08       Impact factor: 5.103

9.  Rapid immunodiagnosis of active cytomegalovirus infection by monoclonal antibody staining of blood leucocytes.

Authors:  W van der Bij; R Torensma; W J van Son; J Anema; J Schirm; A M Tegzess; T H The
Journal:  J Med Virol       Date:  1988-06       Impact factor: 2.327

10.  Identification of the human cytomegalovirus glycoprotein B gene and induction of neutralizing antibodies via its expression in recombinant vaccinia virus.

Authors:  M P Cranage; T Kouzarides; A T Bankier; S Satchwell; K Weston; P Tomlinson; B Barrell; H Hart; S E Bell; A C Minson
Journal:  EMBO J       Date:  1986-11       Impact factor: 11.598
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  3 in total

1.  Cytomegalovirus-specific antibodies to an immediate early antigen and a late membrane antigen and their possible role in controlling secondary cytomegalovirus infection.

Authors:  J van Zanten; M van der Giessen; L H van der Voort; W J van Son; W van der Bij; T H The
Journal:  Clin Exp Immunol       Date:  1991-01       Impact factor: 4.330

2.  Cell surface expression of human cytomegalovirus (HCMV) gp55-116 (gB): use of HCMV-recombinant vaccinia virus-infected cells in analysis of the human neutralizing antibody response.

Authors:  W J Britt; L Vugler; E J Butfiloski; E B Stephens
Journal:  J Virol       Date:  1990-03       Impact factor: 5.103

3.  Fine specificity of the human immune response to the major neutralization epitopes expressed on cytomegalovirus gp58/116 (gB), as determined with human monoclonal antibodies.

Authors:  M Ohlin; V A Sundqvist; M Mach; B Wahren; C A Borrebaeck
Journal:  J Virol       Date:  1993-02       Impact factor: 5.103
  3 in total

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