| Literature DB >> 28285023 |
Jonathan Rabinowitz1, Nina R Schooler2, Ariana Anderson3, Lindsay Ayearst4, David Daniel5, Michael Davidson6, Anzalee Khan7, Bruce Kinon8, Francois Menard9, Lewis Opler10, Mark Opler11, Joanne B Severe12, David Williamson13, Christian Yavorsky14, Jun Zhao15.
Abstract
International Society for CNS Clinical Trials and Methodology convened an expert working-group that assembled consistency/inconsistency flags for the Positive and Negative Syndrome Scale (PANSS). Twenty-four flags were identified and divided based on extent to which they represent error (Possibly, Probably, Very probably or definitely). The flags were applied to assessments derived from the NEWMEDS data repository and the CATIE clinical trial data. Almost 40% of ratings had at least one inconsistency flag raised and 10% had two. Application of flags to clinical rating can improve reliability and validity of trials.Entities:
Mesh：
Year: 2017 PMID： 28285023 PMCID： PMC5662474 DOI： 10.1016/j.schres.2017.03.017
Source DB: PubMed Journal: Schizophr Res ISSN： 0920-9964 Impact factor: 4.939