Literature DB >> 2827708

A neutral sphingomyelinase in spermatozoal plasma membranes.

V T Hinkovska1, D H Petkova, K S Koumanov.   

Abstract

A highly active neutral sphingomyelinase was observed for the first time in ram spermatozoal plasma membranes. The optimal conditions for the enzyme activity are pH 7.4, 40 mM MgCl2, 40 min of incubation, and 267 nmol sphingomyelin. Ca2+ and cholesterol were found to inhibit sphingomyelinase activity.

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Year:  1987        PMID： 2827708     DOI： 10.1139/o87-067

Source DB:  PubMed          Journal:  Biochem Cell Biol        ISSN： 0829-8211            Impact factor:   3.626


  3 in total

1.  An Mn2+-stimulated neutral-sphingomyelinase in seminiferous tubules of immature Wistar rats.

Authors:  P E Raimann; I C Custodio de Souza; E A Bernard; F C Guma
Journal:  Mol Cell Biochem       Date:  1999-11       Impact factor: 3.396

2.  Reproductive pathology and sperm physiology in acid sphingomyelinase-deficient mice.

Authors:  Avigdor Butler; Xingxuan He; Ronald E Gordon; Hai-Shan Wu; Shimon Gatt; Edward H Schuchman
Journal:  Am J Pathol       Date:  2002-09       Impact factor: 4.307

3.  Sperm abnormalities in heterozygous acid sphingomyelinase knockout mice reveal a novel approach for the prevention of genetic diseases.

Authors:  Avigdor Butler; Ronald E Gordon; Shimon Gatt; Edward H Schuchman
Journal:  Am J Pathol       Date:  2007-06       Impact factor: 4.307
  3 in total

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