Literature DB >> 28275072

Strategies for Optimizing the Diagnostic Predictive Value of Clostridium difficile Molecular Diagnostics.

Larry K Kociolek1.   

Abstract

Because nucleic acid amplification tests (NAATs) do not distinguish Clostridium difficile infection (CDI) and asymptomatic C. difficile carriage, the diagnostic predictive value of NAATs is limited when used in patients with a low probability of CDI. In this issue of the Journal of Clinical Microbiology, Truong et al. (J. Clin. Microbiol., 55:1276-1284, 2017, https://doi.org/10.1128/JCM.02319-16) report significant reductions in hospital-onset CDI and oral vancomycin utilization at their institution following implementation of a novel intervention that leveraged their clinical bioinformatics resources to prevent C. difficile testing of stools from patients without clinically significant diarrhea and in patients with recent laxative use.
Copyright © 2017 American Society for Microbiology.

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Year:  2017        PMID: 28275072      PMCID: PMC5405242          DOI: 10.1128/JCM.00147-17

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN: 0095-1137            Impact factor:   5.948


  24 in total

1.  National variability in surveillance, testing, and infection prevention for Clostridium difficile infection in pediatric populations.

Authors:  Larry K Kociolek; Thomas J Sandora
Journal:  Am J Infect Control       Date:  2013-06-19       Impact factor: 2.918

2.  Impact of PCR testing for Clostridium difficile on incident rates and potential on public reporting: is the playing field level?

Authors:  Kimberlee S Fong; Cynthia Fatica; Geraldine Hall; Gary Procop; Susan Schindler; Steven M Gordon; Thomas G Fraser
Journal:  Infect Control Hosp Epidemiol       Date:  2011-09       Impact factor: 3.254

3.  Clinical and Microbiologic Assessment of Cases of Pediatric Community-associated Clostridium difficile Infection Reveals Opportunities for Improved Testing Decisions.

Authors:  Larry K Kociolek; Sameer J Patel; Xiaotian Zheng; Kathleen M Todd; Stanford T Shulman; Dale N Gerding
Journal:  Pediatr Infect Dis J       Date:  2016-02       Impact factor: 2.129

Review 4.  The host immune response to Clostridium difficile.

Authors:  Ciarán P Kelly; Lorraine Kyne
Journal:  J Med Microbiol       Date:  2011-03-17       Impact factor: 2.472

5.  Real-time polymerase chain reaction detection of asymptomatic Clostridium difficile colonization and rising C. difficile-associated disease rates.

Authors:  Hoonmo L Koo; John N Van; Meina Zhao; Xunyan Ye; Paula A Revell; Zhi-Dong Jiang; Carolyn Z Grimes; Diana C Koo; Todd Lasco; Claudia A Kozinetz; Kevin W Garey; Herbert L DuPont
Journal:  Infect Control Hosp Epidemiol       Date:  2014-04-22       Impact factor: 3.254

Review 6.  Breakthroughs in the treatment and prevention of Clostridium difficile infection.

Authors:  Larry K Kociolek; Dale N Gerding
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2016-02-10       Impact factor: 46.802

Review 7.  Diagnosis of Clostridium difficile infection: an ongoing conundrum for clinicians and for clinical laboratories.

Authors:  Carey-Ann D Burnham; Karen C Carroll
Journal:  Clin Microbiol Rev       Date:  2013-07       Impact factor: 26.132

8.  Impact of clinical symptoms on interpretation of diagnostic assays for Clostridium difficile infections.

Authors:  Erik R Dubberke; Zhuolin Han; Linda Bobo; Tiffany Hink; Brenda Lawrence; Susan Copper; Joan Hoppe-Bauer; Carey-Ann D Burnham; William Michael Dunne
Journal:  J Clin Microbiol       Date:  2011-06-22       Impact factor: 5.948

9.  Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America.

Authors:  Stanford T Shulman; Alan L Bisno; Herbert W Clegg; Michael A Gerber; Edward L Kaplan; Grace Lee; Judith M Martin; Chris Van Beneden
Journal:  Clin Infect Dis       Date:  2012-11-15       Impact factor: 9.079

10.  Overdiagnosis of Clostridium difficile Infection in the Molecular Test Era.

Authors:  Christopher R Polage; Clare E Gyorke; Michael A Kennedy; Jhansi L Leslie; David L Chin; Susan Wang; Hien H Nguyen; Bin Huang; Yi-Wei Tang; Lenora W Lee; Kyoungmi Kim; Sandra Taylor; Patrick S Romano; Edward A Panacek; Parker B Goodell; Jay V Solnick; Stuart H Cohen
Journal:  JAMA Intern Med       Date:  2015-11       Impact factor: 21.873

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  10 in total

Review 1.  An Infectious Diseases Perspective on Fecal Microbiota Transplantation for Clostridioides difficile Infection in Children.

Authors:  Jillian M Cotter; Maribeth R Nicholson; Larry K Kociolek
Journal:  J Pediatric Infect Dis Soc       Date:  2019-12-27       Impact factor: 3.164

2.  Healthcare provider diagnostic testing practices for identification of Clostridioides (Clostridium) difficile in children: an Emerging Infections Network survey.

Authors:  Larry K Kociolek; Preeta K Kutty; Philip M Polgreen; Susan E Beekmann
Journal:  Infect Control Hosp Epidemiol       Date:  2019-02-15       Impact factor: 3.254

3.  Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection and Other Conditions in Children: A Joint Position Paper From the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition.

Authors:  Zev H Davidovics; Sonia Michail; Maribeth R Nicholson; Larry K Kociolek; Nikhil Pai; Richard Hansen; Tobias Schwerd; Aldo Maspons; Raanan Shamir; Hania Szajewska; Nikhil Thapar; Tim de Meij; Alexis Mosca; Yvan Vandenplas; Stacy A Kahn; Richard Kellermayer
Journal:  J Pediatr Gastroenterol Nutr       Date:  2019-01       Impact factor: 2.839

4.  Identification of Clostridium innocuum hypothetical protein that is cross-reactive with C. difficile anti-toxin antibodies.

Authors:  K E Cherny; A Balaji; J Mukherjee; Y A Goo; A R Hauser; E Ozer; K J F Satchell; K E R Bachta; T J Kochan; S D Mitra; L K Kociolek
Journal:  Anaerobe       Date:  2022-03-31       Impact factor: 2.837

5.  Clostridium difficile Whole Genome Sequencing Reveals Limited Transmission Among Symptomatic Children: A Single-Center Analysis.

Authors:  Larry K Kociolek; Dale N Gerding; Robyn O Espinosa; Sameer J Patel; Stanford T Shulman; Egon A Ozer
Journal:  Clin Infect Dis       Date:  2018-07-02       Impact factor: 9.079

6.  Whole-genome analysis reveals the evolution and transmission of an MDR DH/NAP11/106 Clostridium difficile clone in a paediatric hospital.

Authors:  Larry K Kociolek; Egon A Ozer; Dale N Gerding; David W Hecht; Sameer J Patel; Alan R Hauser
Journal:  J Antimicrob Chemother       Date:  2018-05-01       Impact factor: 5.790

7.  The Role of Diagnostic Stewardship in Clostridioides difficile Testing: Challenges and Opportunities.

Authors:  Frances J Boly; Kimberly A Reske; Jennie H Kwon
Journal:  Curr Infect Dis Rep       Date:  2020-02-17       Impact factor: 3.725

Review 8.  Advances in the diagnosis and treatment of Clostridium difficile infections.

Authors:  Zhong Peng; Lifen Ling; Charles W Stratton; Chunhui Li; Christopher R Polage; Bin Wu; Yi-Wei Tang
Journal:  Emerg Microbes Infect       Date:  2018-02-07       Impact factor: 7.163

9.  Reducing rates of Clostridium difficile infection by switching to a stand-alone NAAT with clear sampling criteria.

Authors:  E Casari; C De Luca; M Calabrò; C Scuderi; C Daleno; A Ferrario
Journal:  Antimicrob Resist Infect Control       Date:  2018-03-12       Impact factor: 4.887

10.  A low-cost paper-based synthetic biology platform for analyzing gut microbiota and host biomarkers.

Authors:  Melissa K Takahashi; Xiao Tan; Aaron J Dy; Dana Braff; Reid T Akana; Yoshikazu Furuta; Nina Donghia; Ashwin Ananthakrishnan; James J Collins
Journal:  Nat Commun       Date:  2018-08-21       Impact factor: 14.919

  10 in total

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