Literature DB >> 28266738

The how, why and clinical importance of stratum corneum acidification.

Peter M Elias1,2.   

Abstract

In this article, I review the multiple endogenous mechanisms that contribute to the highly acidic pH of normal stratum corneum (SC). Then, I describe how each mechanism potentially impacts specific defensive functions of the SC. Finally, I review the rapidly expanding, clinical implications and potential therapeutic applications of SC acidification.
© 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Keywords:  zzm321990pHzzm321990; acidification; barrier function; stratum corneum

Mesh：

Year:  2017        PMID： 28266738     DOI： 10.1111/exd.13329

Source DB:  PubMed          Journal:  Exp Dermatol        ISSN： 0906-6705            Impact factor:   3.960


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