H Iijima1, T Aoyama2, K Nishitani3, H Ito4, N Fukutani5, T Isho6, E Kaneda7, H Kuroki8, S Matsuda9. 1. Department of Physical Therapy, Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan; Japan Society for the Promotion of Science, Tokyo, Japan. Electronic address: iijimahirotaka@gmail.com. 2. Department of Physical Therapy, Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan. Electronic address: aoyama.tomoki.4e@kyoto-u.ac.jp. 3. Department of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan. Electronic address: nkohei@kuhp.kyoto-u.ac.jp. 4. Department of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan. Electronic address: hiromu@kuhp.kyoto-u.ac.jp. 5. Department of Physical Therapy, Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan. Electronic address: nafukutani@gmail.com. 6. Rehabilitation Center, Fujioka General Hospital, Gunma, Japan. Electronic address: isho.tak@gmail.com. 7. Nozomi Orthopedic Clinic, Hiroshima, Japan. Electronic address: EishiKaneda@nozomi-clinic.jp. 8. Department of Physical Therapy, Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan. Electronic address: kuroki.hiroshi.6s@kyoto-u.ac.jp. 9. Department of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan. Electronic address: smat522@kuhp.kyoto-u.ac.jp.
Abstract
OBJECTIVE: To examine the clinical impact of coexisting lateral osteoarthritis (OA) in knees with mild medial OA. DESIGN: In patients with Kellgren/Lawrence (K/L) grade 2 OA in the medial compartment (n = 100; age: 56-89 years; 80.0% female), anteroposterior knee radiography was used to assess the presence of lateral OA, using grading systems from the Osteoarthritis Research Society International (OARSI) atlas and the K/L classification. The Japanese Knee Osteoarthritis Measure (JKOM), knee range of motion (ROM), and performance-based functional measures (10 m walk, timed up and go and five repetition chair stand maneuvers) were evaluated. The outcomes were compared between patients with and without lateral OA using an analysis of covariance (ANCOVA) or nonparametric rank ANCOVA. Furthermore, ordinal logistic regression analysis was performed, with responses on individual JKOM pain questionnaires as the outcomes and lateral OA as the predictor. RESULTS: Knees with coexisting lateral OA had a significantly worse score of JKOM pain question compared with those without, after adjusting for covariates. The presence of lateral OA was significantly associated with knee pain while ascending/descending stairs and standing. These results were consistent between different definitions of the K/L and OARSI grading systems. The knee ROM and performance-based functional measures were not significantly different between patients with and without lateral OA. CONCLUSION: Knees with concomitant lateral and mild medial OA may be more symptomatic compared to those without lateral OA. These findings might help to define a clinically distinct subgroup based on a simple radiographic finding in mild knee OA.
OBJECTIVE: To examine the clinical impact of coexisting lateral osteoarthritis (OA) in knees with mild medial OA. DESIGN: In patients with Kellgren/Lawrence (K/L) grade 2 OA in the medial compartment (n = 100; age: 56-89 years; 80.0% female), anteroposterior knee radiography was used to assess the presence of lateral OA, using grading systems from the Osteoarthritis Research Society International (OARSI) atlas and the K/L classification. The Japanese Knee Osteoarthritis Measure (JKOM), knee range of motion (ROM), and performance-based functional measures (10 m walk, timed up and go and five repetition chair stand maneuvers) were evaluated. The outcomes were compared between patients with and without lateral OA using an analysis of covariance (ANCOVA) or nonparametric rank ANCOVA. Furthermore, ordinal logistic regression analysis was performed, with responses on individual JKOM pain questionnaires as the outcomes and lateral OA as the predictor. RESULTS: Knees with coexisting lateral OA had a significantly worse score of JKOM pain question compared with those without, after adjusting for covariates. The presence of lateral OA was significantly associated with knee pain while ascending/descending stairs and standing. These results were consistent between different definitions of the K/L and OARSI grading systems. The knee ROM and performance-based functional measures were not significantly different between patients with and without lateral OA. CONCLUSION: Knees with concomitant lateral and mild medial OA may be more symptomatic compared to those without lateral OA. These findings might help to define a clinically distinct subgroup based on a simple radiographic finding in mild knee OA.
Authors: Adrián Borja-Flores; Salvador I Macías-Hernández; Gabriela Hernández-Molina; Andric Perez-Ortiz; Eloy Reyes-Martínez; José Belzazar-Castillo de la Torre; Laura Ávila-Jiménez; María Cristina Vázquez-Bello; Marco Antonio León-Mazón; Janette Furuzawa-Carballeda; Gonzalo Torres-Villalobos; Fernanda Romero-Hernández; Cidronio Albavera-Hernández; Jesús Pérez-Correa; Hilda A Castro-Rocha Journal: Adv Orthop Date: 2020-07-22
Authors: Kade L Paterson; Kim L Bennell; Ben R Metcalf; Penny K Campbell; Fiona McManus; Karen E Lamb; Rana S Hinman Journal: BMJ Open Date: 2022-09-23 Impact factor: 3.006
Authors: Kade L Paterson; Kim L Bennell; Ben R Metcalf; Penny K Campbell; Jessica Kasza; Tim V Wrigley; Rana S Hinman Journal: BMC Musculoskelet Disord Date: 2020-04-15 Impact factor: 2.362