Literature DB >> 28260

Adenylate cyclase of human gastric mucosa. Stimulation of enzyme activity by histamine and catecholamines.

B Simon, H Kather.   

Abstract

Human gastric mucosal adenylate cyclase has been shown to be sensitive to histamine and catecholamines. Stimulation of enzyme activity by histamine and catecholamines were selectively blocked by cimetidine and propranolol, respectively. Combination of both hormones at maximally effective concentrations were additive, indicating that human gastric mucosa contains at least two separate hormone-sensitive adenylate cyclases.

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Year:  1977        PMID： 28260     DOI： 10.1159/000198069

Source DB:  PubMed          Journal:  Digestion        ISSN： 0012-2823            Impact factor:   3.216


  7 in total

Review 1.  [New aspects of catecholamin-receptor interactions. Pathophysiological and clinical implications (author's transl)].

Authors:  H Kather; B Simon
Journal:  Klin Wochenschr       Date:  1978-07-01

2.  Regulation by histamine of cAMP-dependent protein kinase in guinea-pig stomach.

Authors:  O Holian; C T Bombeck; L M Nyhus
Journal:  Agents Actions       Date:  1984-02

3.  Stimulation of human colonic adenylate cyclase.

Authors:  B Simon; H Kather
Journal:  Am J Dig Dis       Date:  1978-01

Review 4.  Adenylyl cyclases in the digestive system.

Authors:  Maria Eugenia Sabbatini; Fred Gorelick; Shannon Glaser
Journal:  Cell Signal       Date:  2014-02-09       Impact factor: 4.315

5.  The effect of cimetidine on cyclic nucleotides in human gastric mucosa.

Authors:  P A Mooney; J M Walters; C F McCarthy; J M O'Donnell
Journal:  Br J Clin Pharmacol       Date:  1981-08       Impact factor: 4.335

6.  Adrenergic stimulation of isolated rat gastric mucosal cells. Effect on adenylate cyclase and 14C-aminopyrine uptake.

Authors:  H J Ruoff; M Wagner; C Günther; S Maśliński
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1982-08       Impact factor: 3.000

7.  Action of histamine and vasoactive intestinal peptide (VIP) on cyclic AMP in gastric glands isolated from human fetal stomach.

Authors:  C Gespach; C Dupont; G Rosselin
Journal:  Experientia       Date:  1981
  7 in total

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