Literature DB >> 28259546

Who is the real 12-HETrE?

Jennifer Yeung1, Michael Holinstat2.   

Abstract

Oxygenases, including lipoxygenases and cytochrome P450s, generate an array of structurally diverse oxylipins that modulate distinct biological responses in mammals. Depending on the source of tissues and enzymes, distinct oxylipins are generated with inherent cellular function. Here, we report structurally different forms of 12-HETrE, with distinct biological function in tissues as well as their derived enzymatic source.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  12(R)-HETrE; 12(S)-HETrE; Arachidonic acid; Dihomo-gamma-linolenic acid; Platelet 12-LOX; Thrombosis

Mesh：

Substances：

Year:  2017        PMID： 28259546      PMCID： PMC5581286          DOI： 10.1016/j.prostaglandins.2017.02.005

Source DB:  PubMed          Journal:  Prostaglandins Other Lipid Mediat        ISSN： 1098-8823            Impact factor:   3.072


  69 in total

1.  Decomposition of unsaturated fatty acid hydroperoxides by hemoglobin: Structures of major products of 13L-hydroperoxy-9,11-octadecadienoic acid.

Authors:  M Hamberg
Journal:  Lipids       Date:  1975-02       Impact factor: 1.880

2.  Activation of the murine EP3 receptor for PGE2 inhibits cAMP production and promotes platelet aggregation.

Authors:  J E Fabre; M Nguyen; K Athirakul; K Coggins; J D McNeish; S Austin; L K Parise; G A FitzGerald; T M Coffman; B H Koller
Journal:  J Clin Invest       Date:  2001-03       Impact factor: 14.808

3.  Activation of FP prostanoid receptor isoforms leads to Rho-mediated changes in cell morphology and in the cell cytoskeleton.

Authors:  K L Pierce; H Fujino; D Srinivasan; J W Regan
Journal:  J Biol Chem       Date:  1999-12-10       Impact factor: 5.157

4.  Inhibition of VEGF expression and corneal neovascularization by siRNA targeting cytochrome P450 4B1.

Authors:  Francesca Seta; Kiran Patil; Lars Bellner; Alexandre Mezentsev; Rowena Kemp; Michael W Dunn; Michal Laniado Schwartzman
Journal:  Prostaglandins Other Lipid Mediat       Date:  2007-05-21       Impact factor: 3.072

5.  12(S)-HETE-induced microvascular endothelial cell retraction results from PKC-dependent rearrangement of cytoskeletal elements and alpha V beta 3 integrins.

Authors:  D G Tang; C A Diglio; K V Honn
Journal:  Prostaglandins       Date:  1993-03

6.  Basal level of human platelet prostaglandins: PGE1 is more elevated than PGE2.

Authors:  M Lagarde; M Dechavanne; M Rigaud; J Durand
Journal:  Prostaglandins       Date:  1979-05

7.  Cloning of a human "epidermal-type" 12-lipoxygenase-related gene and chromosomal localization to 17p13.

Authors:  D Sun; S H Elsea; P I Patel; C D Funk
Journal:  Cytogenet Cell Genet       Date:  1998

8.  NADPH-dependent formation of 15- and 12-hydroxyeicosatrienoic acid from arachidonic acid by rat epidermal microsomes.

Authors:  J Van Wauwe; M C Coene; G Van Nyen; W Cools; J Goossens; L Le Jeune; W Lauwers; P A Janssen
Journal:  Eicosanoids       Date:  1991

9.  Oxidation and keto reduction of 12-hydroxy-5,8,10,14-eicosatetraenoic acids in bovine corneal epithelial microsomes.

Authors:  S Yamamoto; M Nishimura; M S Conners; R A Stoltz; J R Falck; K Chauhan; M Laniado-Schwartzman
Journal:  Biochim Biophys Acta       Date:  1994-01-03

10.  Protein kinase C-dependent effects of 12(S)-HETE on endothelial cell vitronectin receptor and fibronectin receptor.

Authors:  D G Tang; Y Q Chen; C A Diglio; K V Honn
Journal:  J Cell Biol       Date:  1993-05       Impact factor: 10.539
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  2 in total

1.  The Plasma Oxylipin Signature Provides a Deep Phenotyping of Metabolic Syndrome Complementary to the Clinical Criteria.

Authors:  Céline Dalle; Jérémy Tournayre; Malwina Mainka; Alicja Basiak-Rasała; Mélanie Pétéra; Sophie Lefèvre-Arbogast; Jessica Dalloux-Chioccioli; Mélanie Deschasaux-Tanguy; Lucie Lécuyer; Emmanuelle Kesse-Guyot; Léopold K Fezeu; Serge Hercberg; Pilar Galan; Cécilia Samieri; Katarzyna Zatońska; Philip C Calder; Mads Fiil Hjorth; Arne Astrup; André Mazur; Justine Bertrand-Michel; Nils Helge Schebb; Andrzej Szuba; Mathilde Touvier; John W Newman; Cécile Gladine
Journal:  Int J Mol Sci       Date:  2022-10-02       Impact factor: 6.208

Review 2.  Eicosanoids in inflammation in the blood and the vessel.

Authors:  Adriana Yamaguchi; Eliana Botta; Michael Holinstat
Journal:  Front Pharmacol       Date:  2022-09-27       Impact factor: 5.988
  2 in total

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