| Literature DB >> 28255418 |
James R Hayes1, Michael A S Jewett1, Robert J Hamilton1.
Abstract
We present a patient who relapsed symptomatically 28 years post-orchiectomy, initially followed by active surveillance for clinical stage I non-seminomatous germ cell tumour (CSI NSGCT). His relapse was localized to the pelvis, managed with robotic surgery, and achieved a complete resection with tumour markers normalized. We highlight the current Princess Margaret guidelines for followup of CSI NSGCT and discuss the trade-off between lifelong radiographic surveillance to detect the very small risk of late relapse. We discuss the incidence and presentation of late relapse, treatment options, and outcomes, highlighting that these tumours are typically refractory to chemotherapy and can often be managed with surgery alone.Entities:
Year: 2016 PMID: 28255418 PMCID: PMC5325756 DOI: 10.5489/cuaj.3492
Source DB: PubMed Journal: Can Urol Assoc J ISSN: 1911-6470 Impact factor: 1.862