Literature DB >> 28255418

28-year late spermatic cord relapse of a testicular non-seminomatous germ cell tumour, managed robotically.

James R Hayes1, Michael A S Jewett1, Robert J Hamilton1.   

Abstract

We present a patient who relapsed symptomatically 28 years post-orchiectomy, initially followed by active surveillance for clinical stage I non-seminomatous germ cell tumour (CSI NSGCT). His relapse was localized to the pelvis, managed with robotic surgery, and achieved a complete resection with tumour markers normalized. We highlight the current Princess Margaret guidelines for followup of CSI NSGCT and discuss the trade-off between lifelong radiographic surveillance to detect the very small risk of late relapse. We discuss the incidence and presentation of late relapse, treatment options, and outcomes, highlighting that these tumours are typically refractory to chemotherapy and can often be managed with surgery alone.

Entities:  

Year:  2016        PMID: 28255418      PMCID: PMC5325756          DOI: 10.5489/cuaj.3492

Source DB:  PubMed          Journal:  Can Urol Assoc J        ISSN: 1911-6470            Impact factor:   1.862


  17 in total

1.  Germ cell tumour: late recurrence after 43 years.

Authors:  S Mukhtar; J Beatty; S Agrawal; T J Christmas; C Jameson; R A Huddart
Journal:  Ann R Coll Surg Engl       Date:  2011-07       Impact factor: 1.891

Review 2.  Late Relapse of Testicular Germ Cell Tumors.

Authors:  Matthew J O'Shaughnessy; Darren R Feldman; Brett S Carver; Joel Sheinfeld
Journal:  Urol Clin North Am       Date:  2015-06-16       Impact factor: 2.241

3.  Late relapsing stage I nonseminoma.

Authors:  Carmel J Pezaro; Girish Mallesara; Guy C Toner
Journal:  J Clin Oncol       Date:  2008-11-03       Impact factor: 44.544

Review 4.  Late relapse of testis cancer.

Authors:  Yaron Ehrlich; Eli Rosenbaum; Jack Baniel
Journal:  Curr Urol Rep       Date:  2013-10       Impact factor: 3.092

5.  Surveillance for stage I nonseminoma testicular cancer: outcomes and long-term follow-up in a population-based cohort.

Authors:  Gedske Daugaard; Maria Gry Gundgaard; Mette Saksø Mortensen; Mads Agerbæk; Niels Vilstrup Holm; Mikael Rørth; Hans von der Maase; Ib Jarle Christensen; Jakob Lauritsen
Journal:  J Clin Oncol       Date:  2014-09-29       Impact factor: 44.544

6.  A comparative analysis of robotic vs laparoscopic retroperitoneal lymph node dissection for testicular cancer.

Authors:  Kelly T Harris; Michael A Gorin; Mark W Ball; Phillip M Pierorazio; Mohamad E Allaf
Journal:  BJU Int       Date:  2015-05-25       Impact factor: 5.588

7.  Initial series of robot-assisted laparoscopic retroperitoneal lymph node dissection for clinical stage I nonseminomatous germ cell testicular cancer.

Authors:  Stephen B Williams; Clayton S Lau; David Y Josephson
Journal:  Eur Urol       Date:  2011-03-21       Impact factor: 20.096

8.  Patterns of relapse in patients with clinical stage I testicular cancer managed with active surveillance.

Authors:  Christian Kollmannsberger; Torgrim Tandstad; Philippe L Bedard; Gabriella Cohn-Cedermark; Peter W Chung; Michael A Jewett; Tom Powles; Padraig R Warde; Siamak Daneshmand; Andrew Protheroe; Scott Tyldesley; Peter C Black; Kim Chi; Alan I So; Malcom J Moore; Craig R Nichols
Journal:  J Clin Oncol       Date:  2014-08-18       Impact factor: 44.544

9.  Incidence of late-relapse germ cell tumor and outcome to salvage chemotherapy.

Authors:  Ellen A Ronnen; G Varuni Kondagunta; Jennifer Bacik; Stephanie Marion; Dean F Bajorin; Joel Sheinfeld; George J Bosl; Robert J Motzer
Journal:  J Clin Oncol       Date:  2005-10-01       Impact factor: 44.544

10.  Progression detection of stage I nonseminomatous testis cancer on surveillance: implications for the followup protocol.

Authors:  S Sharir; M A Jewett; J F Sturgeon; M Moore; P R Warde; C N Catton; M K Gospodarowicz
Journal:  J Urol       Date:  1999-02       Impact factor: 7.450

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