Literature DB >> 28255010

Heart Failure Incidence and Mortality in the Southern Community Cohort Study.

Elvis A Akwo1, Edmond K Kabagambe1, Thomas J Wang1, Frank E Harrell1, William J Blot1, Michael Mumma1, Deepak K Gupta1, Loren Lipworth2.   

Abstract

BACKGROUND: There is a paucity of data on heart failure (HF) incidence among low-income and minority populations. Our objective was to investigate HF incidence and post-HF survival by race and sex among low-income adults in the southeastern United States. METHODS AND
RESULTS: Participants were 27 078 white and black men and women enrolled during 2002 to 2009 in the SCCS (Southern Community Cohort Study) who had no history of HF and were receiving Centers for Medicare and Medicaid Services. Incident HF diagnoses through December 31, 2010 were ascertained using International Classification of Diseases 9th Revision codes 428.x via linkage with Centers for Medicare and Medicaid Services research files. Most participants were black (68.8%), women (62.6%), and earned <$15 000/y (69.7%); mean age was 55.5 (10.4) years. Risk factors for HF were common: hypertension (62.5%), diabetes mellitus (26.5%), myocardial infarction (8.6%), and obesity (44.8%). Over a median follow-up of 5.2 years, 4341 participants were diagnosed with HF. The age-standardized incidence rates were 34.8, 37.3, 34.9, and 35.6 /1000 person-years in white women, white men, black men, and black women, respectively, remarkably higher than previously reported. Among HF cases, 952 deaths occurred over a median follow-up of 2.3 years. Men had lower survival; hazard ratios and 95% confidence intervals were 1.63 (1.27-2.08), 1.38 (1.11-1.72), and 0.90 (0.73-1.12) for white men, black men, and black women compared with white women.
CONCLUSIONS: In this low-income population, HF incidence was higher for all race-sex groups than previously reported in other cohorts. The SCCS is a unique resource to investigate determinants of HF risk in a segment of the population underrepresented in other existing cohorts.
© 2017 American Heart Association, Inc.

Entities:  

Keywords:  epidemiology; heart failure; incidence; population; survival

Mesh:

Year:  2017        PMID: 28255010      PMCID: PMC5365148          DOI: 10.1161/CIRCHEARTFAILURE.116.003553

Source DB:  PubMed          Journal:  Circ Heart Fail        ISSN: 1941-3289            Impact factor:   8.790


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1.  Neighborhood Deprivation Predicts Heart Failure Risk in a Low-Income Population of Blacks and Whites in the Southeastern United States.

Authors:  Elvis A Akwo; Edmond K Kabagambe; Frank E Harrell; William J Blot; Justin M Bachmann; Thomas J Wang; Deepak K Gupta; Loren Lipworth
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2.  Race and Sex Differences in Modifiable Risk Factors and Incident Heart Failure.

Authors:  Danielle M Kubicki; Meng Xu; Elvis A Akwo; Debra Dixon; Daniel Muñoz; William J Blot; Thomas J Wang; Loren Lipworth; Deepak K Gupta
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4.  Relation of the Dietary Approaches to Stop Hypertension Dietary Pattern to Heart Failure Risk and Socioeconomic Status (from the Southern Community Cohort Study).

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Authors:  Nicholas R Jones; Andrea K Roalfe; Ibiye Adoki; F D Richard Hobbs; Clare J Taylor
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