| Literature DB >> 28251093 |
Pedro Naranjo-Bonilla1, Rafael Giménez-Gómez1, David Ríos-Jiménez1, María Luísa Varas-Fabra1, María Del Carmen Muñoz-Villanueva2, Rocío García-Catalán1, Pilar Font-Ugalde3, María Soledad Poblador-Fernández4, José Luís Lancho-Alonso4, José María Gallardo-Galera1.
Abstract
The lamina cribrosa thickness (LCT) could be affected by dynamic changes in its structure. Using Spectral-domain-optical coherence tomography (SD-OCT), we have studied the behaviour of the laminar region in 14 young subjects over 24h. Significant changes in LCT were observed, depending on the time at which the measurement was taken, with the maximum thickness being observed at 7.30 p.m., and the minimum at 7.30 a.m. This finding could suggests a circadian pattern in the LCT thickness in healthy subjects, which could have implications for the classification, diagnosis and prognosis of both normal and glaucomatous subjects.Entities:
Keywords: glaucoma; lamina cribrosa; laminar region; optical coherence tomography; twenty-four-hours
Year: 2017 PMID： 28251093 PMCID： PMC5313557 DOI： 10.18240/ijo.2017.02.20
Source DB: PubMed Journal: Int J Ophthalmol ISSN： 2222-3959 Impact factor: 1.779