Literature DB >> 2824670

Identification of human papillomavirus type 16 E7 protein by monoclonal antibodies.

T Oltersdorf1, K Seedorf, W Röwekamp, L Gissmann.   

Abstract

A number of human papillomavirus (HPV) type 16 proteins have recently been identified in human cervical carcinoma cell lines using polyclonal antisera against papillomavirus gene products expressed in Escherichia coli. E7 protein has been found to be the most abundant papillomavirus protein in these cells. Here we describe a panel of monoclonal antibodies recognizing a 15K Mr non-glycosylated cytoplasmic HPV-16 E7 protein. One of the antibodies cross-reacted with HPV-18 E7 protein.

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Year:  1987        PMID： 2824670     DOI： 10.1099/0022-1317-68-11-2933

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  11 in total

1.  Intranuclear localization of human papillomavirus 16 E7 during transformation and preferential binding of E7 to the Rb family member p130.

Authors:  K Smith-McCune; D Kalman; C Robbins; S Shivakumar; L Yuschenkoff; J M Bishop
Journal:  Proc Natl Acad Sci U S A       Date:  1999-06-08       Impact factor: 11.205

2.  Production and characterisation of a monoclonal antibody to human papillomavirus type 16 using recombinant vaccinia virus.

Authors:  C S McLean; M J Churcher; J Meinke; G L Smith; G Higgins; M Stanley; A C Minson
Journal:  J Clin Pathol       Date:  1990-06       Impact factor: 3.411

3.  A point mutational analysis of human papillomavirus type 16 E7 protein.

Authors:  C Edmonds; K H Vousden
Journal:  J Virol       Date:  1989-06       Impact factor: 5.103

4.  Influence of chromosomal integration on glucocorticoid-regulated transcription of growth-stimulating papillomavirus genes E6 and E7 in cervical carcinoma cells.

Authors:  M von Knebel Doeberitz; T Bauknecht; D Bartsch; H zur Hausen
Journal:  Proc Natl Acad Sci U S A       Date:  1991-02-15       Impact factor: 11.205

5.  Expression of human papilloma virus type 16 antigens, specific targeting as well as formation of virus-like particles by HSV-1 amplicon vectors.

Authors:  Sabine Schenck; Elke Kehm; Alberto L Epstein; Hanswalter Zentgraf; Martin Müller; Charles W Knopf
Journal:  Virus Genes       Date:  2008-06-12       Impact factor: 2.332

6.  Antibodies against linear and conformational epitopes of the human papillomavirus (HPV) type 16 E6 and E7 oncoproteins in sera of cervical cancer patients.

Authors:  I Nindl; L Benitez-Bribiesca; J Berumen; N Farmanara; S Fisher; G Gross; L Lopez-Carillo; M Müller; M Tommasino; A Vazquez-Curiel
Journal:  Arch Virol       Date:  1994       Impact factor: 2.574

7.  The region of the HPV E7 oncoprotein homologous to adenovirus E1a and Sv40 large T antigen contains separate domains for Rb binding and casein kinase II phosphorylation.

Authors:  M S Barbosa; C Edmonds; C Fisher; J T Schiller; D R Lowy; K H Vousden
Journal:  EMBO J       Date:  1990-01       Impact factor: 11.598

8.  Continued expression of HPV-16 E7 protein is required for maintenance of the transformed phenotype of cells co-transformed by HPV-16 plus EJ-ras.

Authors:  T Crook; J P Morgenstern; L Crawford; L Banks
Journal:  EMBO J       Date:  1989-02       Impact factor: 11.598

Review 9.  Testing for human papillomavirus: basic pathobiology of infection, methodologies, and implications for clinical use.

Authors:  D C Wilbur; M H Stoler
Journal:  Yale J Biol Med       Date:  1991 Mar-Apr

10.  Comparison of the in vitro transforming activities of human papillomavirus types.

Authors:  A Storey; D Pim; A Murray; K Osborn; L Banks; L Crawford
Journal:  EMBO J       Date:  1988-06       Impact factor: 11.598
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