Literature DB >> 28242959

Is Laparoscopic Power Morcellation of Fibroids a Cardinal Sin in 2017?

Gautam N Allahbadia1.   

Abstract

The diagnosis of an unsuspected leiomyosarcoma after hysterectomy for the treatment of a presumed benign leiomyoma is a rare but highly clinically significant event. In order to facilitate removal of large uterine specimens using a minimally invasive surgical approach, morcellation with extraction in pieces is often performed. In the event of unsuspected malignancy, this may result in abdominal dispersion of the tumor and contribute to poorer survival. Modern surgical innovations always work toward improving minimally invasive strategies. Laparoscopy, rooted in practices for years, supplanted laparotomy for many indications. For extraction of large uteri, morcellation is currently the only way to externalize surgical specimens (myomas, uteri), without increasing the skin opening while allowing to reduce postoperative complications when compared to laparotomy. However, in 2014, the Food and Drug Administration warned against the use of uterine morcellation because of an oncological risk. Some practicing academicians have challenged this recommendation. The incidence of uterine sarcomas is still poorly identified and preoperative diagnostic facilities remain inadequate. The small number of retrospective studies currently available do not reinforce any recommendation. The evaluation of morcellation devices and the improvement of preoperative diagnostic modalities (Imaging, preoperative Biopsy) are being improvised continually so as to minimize the oncological risks. Even during conventional myomectomy, tissue spillage occurs during resection of leiomyoma(s). Adverse oncologic outcomes of tissue morcellation should be mitigated through improved patient selection, preoperative investigations, and novel techniques that minimize tissue dispersion. Preoperative endometrial biopsy and cervical assessment to avoid morcellation of potentially detectable malignant and premalignant conditions is recommended.

Entities:  

Year:  2017        PMID: 28242959      PMCID: PMC5306108          DOI: 10.1007/s13224-017-0970-y

Source DB:  PubMed          Journal:  J Obstet Gynaecol India        ISSN: 0975-6434


  24 in total

1.  Practice patterns and postoperative complications before and after US Food and Drug Administration safety communication on power morcellation.

Authors:  John A Harris; Carolyn W Swenson; Shitanshu Uppal; Neil Kamdar; Nichole Mahnert; Sawsan As-Sanie; Daniel M Morgan
Journal:  Am J Obstet Gynecol       Date:  2015-08-24       Impact factor: 8.661

2.  Effects of morcellation on long-term outcomes in patients with uterine leiomyosarcoma.

Authors:  W Nemec; E C Inwald; S Buchholz; M Klinkhammer Schalke; M Gerken; O Ortmann
Journal:  Arch Gynecol Obstet       Date:  2016-04-22       Impact factor: 2.344

3.  Laparoscopic hysterectomy with morcellation vs abdominal hysterectomy for presumed fibroids: an updated decision analysis following the 2014 Food and Drug Administration safety communications.

Authors:  Matthew T Siedhoff; Kemi M Doll; Daniel L Clarke-Pearson; Sarah E Rutstein
Journal:  Am J Obstet Gynecol       Date:  2016-11-24       Impact factor: 8.661

4.  Incidental power morcellation of malignancy: a retrospective cohort study.

Authors:  Kerry Graebe; Arlene Garcia-Soto; Michael Aziz; Vanessa Valarezo; Paul B Heller; Nana Tchabo; Daniel H Tobias; Charbel Salamon; Joseph Ramieri; Craig Dise; Brian M Slomovitz
Journal:  Gynecol Oncol       Date:  2014-11-26       Impact factor: 5.482

5.  Disseminated leiomyoma cells can be identified following conventional myomectomy.

Authors:  E M Sandberg; L van den Haak; T Bosse; F W Jansen
Journal:  BJOG       Date:  2016-08-17       Impact factor: 6.531

6.  Uterine sarcomas and parasitic myomas after laparoscopic hysterectomy with power morcellation.

Authors:  Jasmine Tan-Kim; Katherine A Hartzell; Caryl S Reinsch; Cristina H O'Day; John S Kennedy; Shawn A Menefee; Terry A Harrison
Journal:  Am J Obstet Gynecol       Date:  2014-12-11       Impact factor: 8.661

7.  Clinical Characteristics and Prognosis of Unexpected Uterine Sarcoma After Hysterectomy for Presumed Myoma With and Without Transvaginal Scalpel Morcellation.

Authors:  Jiaren Zhang; Ting Li; Junji Zhang; Lan Zhu; Jinghe Lang; Jinhua Leng
Journal:  Int J Gynecol Cancer       Date:  2016-03       Impact factor: 3.437

8.  U.S. Food and Drug Administration's Guidance Regarding Morcellation of Leiomyomas: Well-Intentioned, But Is It Harmful for Women?

Authors:  William H Parker; Andrew M Kaunitz; Elizabeth A Pritts; David L Olive; Eva Chalas; Daniel L Clarke-Pearson; Jonathan S Berek
Journal:  Obstet Gynecol       Date:  2016-01       Impact factor: 7.661

9.  Incidence of occult leiomyosarcoma in presumed morcellation cases: a database study.

Authors:  Ana M Rodriguez; Mehmet R Asoglu; Muhammet Erdal Sak; Alai Tan; Mostafa A Borahay; Gokhan S Kilic
Journal:  Eur J Obstet Gynecol Reprod Biol       Date:  2015-11-28       Impact factor: 2.831

10.  RETIRED: Technical update on tissue morcellation during gynaecologic surgery: its uses, complications, and risks of unsuspected malignancy.

Authors:  Sukhbir S Singh; Stephanie Scott; Olga Bougie; Nicholas Leyland
Journal:  J Obstet Gynaecol Can       Date:  2015-01
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  1 in total

1.  Disseminated ovarian granulosa cell tumor after laparoscopic surgery: Two case reports.

Authors:  Man-Hua Cui; Xi-Wen Zhang; Li-Ping Zhao; Shu-Yan Liu; Yan Jia
Journal:  Medicine (Baltimore)       Date:  2021-04-16       Impact factor: 1.817

  1 in total

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