Literature DB >> 2823700

Mapping of trimethoprim resistance genes from epidemiologically related plasmids.

I G Campbell1, B J Mee.   

Abstract

Trimethoprim resistance dihydrofolate reductase genes from plasmids known to be exchanging between human and animal populations were mapped. The dihydrofolate reductase gene has been highly conserved in all plasmids, but differences in the flanking regions provide evidence that the most recent exchange of plasmids between the two ecosystems has been from animals to humans.

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Year:  1987        PMID： 2823700      PMCID： PMC174960          DOI： 10.1128/AAC.31.9.1440

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  7 in total

1.  Isolation of a small DNA fragment carrying the gene for a dihydrofolate reductase from a trimethoprim resistance factor.

Authors:  J W Zolg; U J Hänggi; H G Zachau
Journal:  Mol Gen Genet       Date:  1978-08-04

2.  Nucleotide sequence of the dihydrofolate-reductase gene borne by the plasmid R67 and conferring methotrexate resistance.

Authors:  N Brisson; T Hohn
Journal:  Gene       Date:  1984-05       Impact factor: 3.688

3.  Trimethoprim resistance in multiple genera of Enterobacteriaceae at a U.S. hospital: spread of the type II dihydrofolate reductase gene by a single plasmid.

Authors:  K H Mayer; M E Fling; J D Hopkins; T F O'Brien
Journal:  J Infect Dis       Date:  1985-05       Impact factor: 5.226

4.  Evolution and spread of IncFIV plasmids conferring resistance to trimethoprim.

Authors:  I G Campbell; B J Mee; S M Nikoletti
Journal:  Antimicrob Agents Chemother       Date:  1986-05       Impact factor: 5.191

5.  Distribution of genes for trimethoprim and gentamicin resistance in bacteria and their plasmids in a general hospital.

Authors:  N Datta; S Dacey; V Hughes; S Knight; H Richards; G Williams; M Casewell; K P Shannon
Journal:  J Gen Microbiol       Date:  1980-06

6.  DNA sequence of a plasmid-encoded dihydrofolate reductase.

Authors:  G Swift; B J McCarthy; F Heffron
Journal:  Mol Gen Genet       Date:  1981

7.  Monitoring of plasmid-encoded, trimethoprim-resistant dihydrofolate reductase genes: detection of a new resistant enzyme.

Authors:  M E Fling; L Walton; L P Elwell
Journal:  Antimicrob Agents Chemother       Date:  1982-11       Impact factor: 5.191
  7 in total
  2 in total

1.  High genetic homology between plasmids of human and animal origins conferring resistance to the aminoglycosides gentamicin and apramycin.

Authors:  E Chaslus-Dancla; P Pohl; M Meurisse; M Marin; J P Lafont
Journal:  Antimicrob Agents Chemother       Date:  1991-03       Impact factor: 5.191

2.  Spread of a newly found trimethoprim resistance gene, dhfrIX, among porcine isolates and human pathogens.

Authors:  C Jansson; A Franklin; O Sköld
Journal:  Antimicrob Agents Chemother       Date:  1992-12       Impact factor: 5.191
  2 in total

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