Literature DB >> 28225438

Levels of Intracellular Phosphorylated Tenofovir and Emtricitabine Correlate With Natural Substrate Concentrations in Peripheral Blood Mononuclear Cells of Persons Prescribed Daily Oral Truvada for HIV Pre-exposure Prophylaxis.

Richard E Haaland1, Angela Holder, Chou-Pong Pau, Alison Swaims-Kohlmeier, Carolyn Dawson, Dawn K Smith, Tebogo M Segolodi, Michael C Thigpen, Lynn A Paxton, Teresa L Parsons, Craig W Hendrix, Clyde E Hart.   

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Year:  2017        PMID： 28225438      PMCID： PMC5472483          DOI： 10.1097/QAI.0000000000001324

Source DB:  PubMed          Journal:  J Acquir Immune Defic Syndr        ISSN： 1525-4135            Impact factor:   3.731


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  14 in total

Review 1.  Preexposure prophylaxis for HIV prevention: where have we been and where are we going?

Authors:  Jared M Baeten; Jessica E Haberer; Albert Y Liu; Nirupama Sista
Journal:  J Acquir Immune Defic Syndr       Date:  2013-07       Impact factor: 3.731

2.  A Translational Pharmacology Approach to Predicting Outcomes of Preexposure Prophylaxis Against HIV in Men and Women Using Tenofovir Disoproxil Fumarate With or Without Emtricitabine.

Authors:  Mackenzie L Cottrell; Kuo H Yang; Heather M A Prince; Craig Sykes; Nicole White; Stephanie Malone; Evan S Dellon; Ryan D Madanick; Nicholas J Shaheen; Michael G Hudgens; Jacob Wulff; Kristine B Patterson; Julie A E Nelson; Angela D M Kashuba
Journal:  J Infect Dis       Date:  2016-02-24       Impact factor: 5.226

3.  Uptake of pre-exposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men: a cohort study.

Authors:  Robert M Grant; Peter L Anderson; Vanessa McMahan; Albert Liu; K Rivet Amico; Megha Mehrotra; Sybil Hosek; Carlos Mosquera; Martin Casapia; Orlando Montoya; Susan Buchbinder; Valdilea G Veloso; Kenneth Mayer; Suwat Chariyalertsak; Linda-Gail Bekker; Esper G Kallas; Mauro Schechter; Juan Guanira; Lane Bushman; David N Burns; James F Rooney; David V Glidden
Journal:  Lancet Infect Dis       Date:  2014-07-22       Impact factor: 25.071

4.  Intracellular Tenofovir and Emtricitabine Anabolites in Genital, Rectal, and Blood Compartments from First Dose to Steady State.

Authors:  Sharon M Seifert; Xinhui Chen; Amie L Meditz; Jose R Castillo-Mancilla; Edward M Gardner; Julie A Predhomme; Carolyn Clayton; Gregory Austin; Brent E Palmer; Jia-Hua Zheng; Brandon Klein; Becky J Kerr; L Anthony Guida; Caitlin Rower; Joseph E Rower; Jennifer J Kiser; Lane R Bushman; Samantha MaWhinney; Peter L Anderson
Journal:  AIDS Res Hum Retroviruses       Date:  2016-09-19       Impact factor: 2.205

5.  Emtricitabine-tenofovir concentrations and pre-exposure prophylaxis efficacy in men who have sex with men.

Authors:  Peter L Anderson; David V Glidden; Albert Liu; Susan Buchbinder; Javier R Lama; Juan Vicente Guanira; Vanessa McMahan; Lane R Bushman; Martín Casapía; Orlando Montoya-Herrera; Valdilea G Veloso; Kenneth H Mayer; Suwat Chariyalertsak; Mauro Schechter; Linda-Gail Bekker; Esper Georges Kallás; Robert M Grant
Journal:  Sci Transl Med       Date:  2012-09-12       Impact factor: 17.956

6.  Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana.

Authors:  Michael C Thigpen; Poloko M Kebaabetswe; Lynn A Paxton; Dawn K Smith; Charles E Rose; Tebogo M Segolodi; Faith L Henderson; Sonal R Pathak; Fatma A Soud; Kata L Chillag; Rodreck Mutanhaurwa; Lovemore Ian Chirwa; Michael Kasonde; Daniel Abebe; Evans Buliva; Roman J Gvetadze; Sandra Johnson; Thom Sukalac; Vasavi T Thomas; Clyde Hart; Jeffrey A Johnson; C Kevin Malotte; Craig W Hendrix; John T Brooks
Journal:  N Engl J Med       Date:  2012-07-11       Impact factor: 91.245

7.  On-line coupling of anion exchange and ion-pair chromatography for measurement of intracellular triphosphate metabolites of reverse transcriptase inhibitors.

Authors:  Zsuzsanna Kuklenyik; Amy Martin; Chou-Pong Pau; Angela Holder; Ae S Youngpairoj; Qi Zheng; Mian-Er Cong; J Gerardo Garcia-Lerma; Walid Heneine; James L Pirkle; John R Barr
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2009-09-11       Impact factor: 3.205

8.  Cervicovaginal and Rectal Fluid as a Surrogate Marker of Antiretroviral Tissue Concentration: Implications for Clinical Trial Design.

Authors:  Mackenzie L Cottrell; Heather M A Prince; Andrew Allmon; Katie R Mollan; Michael G Hudgens; Craig Sykes; Nicole White; Stephanie Malone; Evan S Dellon; Ryan D Madanick; Nicholas J Shaheen; Kristine B Patterson; Angela D M Kashuba
Journal:  J Acquir Immune Defic Syndr       Date:  2016-08-15       Impact factor: 3.731

9.  Dose Frequency Ranging Pharmacokinetic Study of Tenofovir-Emtricitabine After Directly Observed Dosing in Healthy Volunteers to Establish Adherence Benchmarks (HPTN 066).

Authors:  Craig W Hendrix; Adriana Andrade; Namandjé N Bumpus; Angela D Kashuba; Mark A Marzinke; Ayana Moore; Peter L Anderson; Lane R Bushman; Edward J Fuchs; Ilene Wiggins; Christine Radebaugh; Heather A Prince; Rahul P Bakshi; Ruili Wang; Paul Richardson; Eugenie Shieh; Laura McKinstry; Xin Li; Deborah Donnell; Vanessa Elharrar; Kenneth H Mayer; Kristine B Patterson
Journal:  AIDS Res Hum Retroviruses       Date:  2015-10-15       Impact factor: 2.205

10.  Metabolism of tenofovir and didanosine in quiescent or stimulated human peripheral blood mononuclear cells.

Authors:  Brian L Robbins; Carrie K Wilcox; Arnold Fridland; John H Rodman
Journal:  Pharmacotherapy       Date:  2003-06       Impact factor: 4.705
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  3 in total

Review 1.  Topical Microbicides in HIV Prevention: State of the Promise.

Authors:  Jared M Baeten; Craig W Hendrix; Sharon L Hillier
Journal:  Annu Rev Med       Date:  2019-10-15       Impact factor: 13.739

2.  Plasma and intracellular pharmacokinetics of tenofovir disoproxil fumarate and emtricitabine in transgender women receiving feminizing hormone therapy.

Authors:  Lauren R Cirrincione; Anthony T Podany; Joshua P Havens; Sara H Bares; Shetty Ravi Dyavar; Yeongjin Gwon; Tanner M Johnson; N Jean Amoura; Courtney V Fletcher; Kimberly K Scarsi
Journal:  J Antimicrob Chemother       Date:  2020-05-01       Impact factor: 5.790

3.  Repeated rectal application of a hyperosmolar lubricant is associated with microbiota shifts but does not affect PrEP drug concentrations: results from a randomized trial in men who have sex with men.

Authors:  Richard E Haaland; Jeffrey Fountain; Yingtian Hu; Angela Holder; Chuong Dinh; LaShonda Hall; Nicole A Pescatore; Sheila Heeke; Clyde E Hart; Jiahui Xu; Yi-Juan Hu; Colleen F Kelley
Journal:  J Int AIDS Soc       Date:  2018-10       Impact factor: 5.396
  3 in total

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