Literature DB >> 28222520

Interactive Effects of Dementia Severity and Comorbidities on Medicare Expenditures.

Carolyn W Zhu1,2, Stephanie Cosentino3, Katherine A Ornstein1, Yian Gu3, Howard Andrews4, Yaakov Stern3.   

Abstract

BACKGROUND: Few studies have examined how dementia and comorbidities may interact to affect healthcare expenditures.
OBJECTIVE: To examine whether effects of dementia severity on Medicare expenditures differed for individuals with different levels of comorbidities.
METHODS: Data are drawn from the Washington Heights-Inwood Columbia Aging Project (WHICAP). Comprehensive clinical assessments of dementia severity were systematically carried out at ∼18 month intervals. Dementia severity was measured by Clinical Dementia Rating (CDR). Comorbidities were measured by a modified Elixhauser comorbidities index. Generalized linear models examined effects of dementia severity, comorbidities, and their interactions on Medicare expenditures (1999-2010).
RESULTS: At baseline, 1,280 subjects were dementia free (CDR = 0, 66.4%), 490 had very mild dementia (CDR = 0.5, 25.4%), 108 had mild dementia (CDR = 1, 5.6%), and 49 had moderate/severe dementia (CDR = 2/3, 2.5%). Average annual Medicare expenditures for individuals with moderate/severe dementia were more than twice as high as those who were dementia free (CDR = 0: $9,108, CDR = 0.5/1: $11,664, CDR≥2: $19,604, p < 0.01). Expenditures were approximately 10 times higher among those with≥3 comorbidities than among those with no comorbidities ($2,612 for those with no comorbidities, to $6,109 for those with 1, $10,656 for those with 2, and $30,244 for those with≥3 comorbidities, p < 0.001). Dementia severity was associated with higher expenditures, but comorbidities were the most important predictor of expenditures. We did not find strong interaction effects between number of comorbidities and dementia severity.
CONCLUSIONS: Increasing dementia severity and higher comorbidities are associated with higher Medicare expenditures. Care of individuals with dementia should focus on management of comorbidities.

Entities:  

Keywords:  Health expenditure; Medicare; comorbidities; economics; longitudinal analysis

Mesh:

Year:  2017        PMID: 28222520      PMCID: PMC5461168          DOI: 10.3233/JAD-161077

Source DB:  PubMed          Journal:  J Alzheimers Dis        ISSN: 1387-2877            Impact factor:   4.472


  46 in total

1.  The relative effect of Alzheimer's disease and related dementias, disability, and comorbidities on cost of care for elderly persons.

Authors:  D H Taylor; M Schenkman; J Zhou; F A Sloan
Journal:  J Gerontol B Psychol Sci Soc Sci       Date:  2001-09       Impact factor: 4.077

2.  Influence of leisure activity on the incidence of Alzheimer's disease.

Authors:  N Scarmeas; G Levy; M X Tang; J Manly; Y Stern
Journal:  Neurology       Date:  2001-12-26       Impact factor: 9.910

3.  Diagnosis of dementia in a heterogeneous population. Development of a neuropsychological paradigm-based diagnosis of dementia and quantified correction for the effects of education.

Authors:  Y Stern; H Andrews; J Pittman; M Sano; T Tatemichi; R Lantigua; R Mayeux
Journal:  Arch Neurol       Date:  1992-05

4.  Interrater reliability of extrapyramidal signs in a group assessed for dementia.

Authors:  M Richards; K Marder; K Bell; G Dooneief; R Mayeux; Y Stern
Journal:  Arch Neurol       Date:  1991-11

5.  Multiple chronic conditions among Medicare beneficiaries: state-level variations in prevalence, utilization, and cost, 2011.

Authors:  Kimberly A Lochner; Richard A Goodman; Samual Posner; Anand Parekh
Journal:  Medicare Medicaid Res Rev       Date:  2013-07-23

6.  The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects.

Authors:  G Blessed; B E Tomlinson; M Roth
Journal:  Br J Psychiatry       Date:  1968-07       Impact factor: 9.319

7.  Burden of Alzheimer's disease and association with negative health outcomes.

Authors:  Daniel C Malone; Trent P McLaughlin; Peter M Wahl; Christopher Leibman; H Michael Arrighi; Mark J Cziraky; Lisa M Mucha
Journal:  Am J Manag Care       Date:  2009-08       Impact factor: 2.229

8.  Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study.

Authors:  Karen Barnett; Stewart W Mercer; Michael Norbury; Graham Watt; Sally Wyke; Bruce Guthrie
Journal:  Lancet       Date:  2012-05-10       Impact factor: 79.321

Review 9.  Review of statistical methods for analysing healthcare resources and costs.

Authors:  Borislava Mihaylova; Andrew Briggs; Anthony O'Hagan; Simon G Thompson
Journal:  Health Econ       Date:  2010-08-27       Impact factor: 3.046

Review 10.  Comorbidity and dementia: a scoping review of the literature.

Authors:  Frances Bunn; Anne-Marie Burn; Claire Goodman; Greta Rait; Sam Norton; Louise Robinson; Johan Schoeman; Carol Brayne
Journal:  BMC Med       Date:  2014-10-31       Impact factor: 8.775

View more
  10 in total

1.  Medicare Expenditures and Health Care Utilization in a Multiethnic Community-based Population With Dementia From Incidence to Death.

Authors:  Katherine A Ornstein; Carolyn W Zhu; Evan Bollens-Lund; Melissa D Aldridge; Howard Andrews; Nicole Schupf; Yaakov Stern
Journal:  Alzheimer Dis Assoc Disord       Date:  2018 Oct-Dec       Impact factor: 2.703

2.  Extent and Predictors of Potentially Inappropriate Antidepressant Use Among Older Adults With Dementia and Major Depressive Disorder.

Authors:  Sandipan Bhattacharjee; Jeannie K Lee; Asad E Patanwala; Nina Vadiei; Daniel C Malone; Shannon M Knapp; Wei-Hsuan Lo-Ciganic; William J Burke
Journal:  Am J Geriatr Psychiatry       Date:  2019-02-07       Impact factor: 4.105

Review 3.  Mind the gaps: What we don't know about cognitive impairment in essential tremor.

Authors:  Elan D Louis; Jillian L Joyce; Stephanie Cosentino
Journal:  Parkinsonism Relat Disord       Date:  2019-03-01       Impact factor: 4.891

4.  Extent and Factors Associated with Adherence to Antidepressant Treatment During Acute and Continuation Phase Depression Treatment Among Older Adults with Dementia and Major Depressive Disorder.

Authors:  Sandipan Bhattacharjee; Jeannie K Lee; Nina Vadiei; Asad E Patanwala; Daniel C Malone; Shannon M Knapp; Wei-Hsuan Lo-Ciganic; William J Burke
Journal:  Neuropsychiatr Dis Treat       Date:  2020-06-08       Impact factor: 2.570

5.  Increased risk of neurodegenerative dementia in women with migraines: A nested case-control study using a national sample cohort.

Authors:  Sang-Yeon Lee; Jae-Sung Lim; Dong Jun Oh; Il Gyu Kong; Hyo Geun Choi
Journal:  Medicine (Baltimore)       Date:  2019-02       Impact factor: 1.817

6.  Alzheimer's disease medication and risk of all-cause mortality and all-cause hospitalization: A retrospective cohort study.

Authors:  Sandipan Bhattacharjee; Asad E Patanwala; Wei-Hsuan Lo-Ciganic; Daniel C Malone; Jeannie K Lee; Shannon M Knapp; Terri Warholak; William J Burke
Journal:  Alzheimers Dement (N Y)       Date:  2019-07-10

7.  The comorbidity conditions and polypharmacy in elderly patients with mental illness in a middle income country: a cross-sectional study⋆.

Authors:  Juliana Dias de Lima; Ivan Abdalla Teixeira; Felipe de Oliveira Silva; Andrea Camaz Deslandes
Journal:  IBRO Rep       Date:  2020-07-16

Review 8.  Exploring costs, cost components, and associated factors among people with dementia approaching the end of life: A systematic review.

Authors:  Javiera Leniz; Deokhee Yi; Emel Yorganci; Lesley E Williamson; Trisha Suji; Rachel Cripps; Irene J Higginson; Katherine E Sleeman
Journal:  Alzheimers Dement (N Y)       Date:  2021-09-14

9.  Economic and caregiver impact of Alzheimer's disease across the disease spectrum: a cohort study.

Authors:  Virginie Dauphinot; Michele Potashman; Mihaela Levitchi-Benea; Ray Su; Ivana Rubino; Pierre Krolak-Salmon
Journal:  Alzheimers Res Ther       Date:  2022-02-12       Impact factor: 6.982

Review 10.  Dementia prevention, intervention, and care: 2020 report of the Lancet Commission.

Authors:  Gill Livingston; Jonathan Huntley; Andrew Sommerlad; David Ames; Clive Ballard; Sube Banerjee; Carol Brayne; Alistair Burns; Jiska Cohen-Mansfield; Claudia Cooper; Sergi G Costafreda; Amit Dias; Nick Fox; Laura N Gitlin; Robert Howard; Helen C Kales; Mika Kivimäki; Eric B Larson; Adesola Ogunniyi; Vasiliki Orgeta; Karen Ritchie; Kenneth Rockwood; Elizabeth L Sampson; Quincy Samus; Lon S Schneider; Geir Selbæk; Linda Teri; Naaheed Mukadam
Journal:  Lancet       Date:  2020-07-30       Impact factor: 79.321

  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.