Literature DB >> 22579043

Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study.

Karen Barnett1, Stewart W Mercer, Michael Norbury, Graham Watt, Sally Wyke, Bruce Guthrie.   

Abstract

BACKGROUND: Long-term disorders are the main challenge facing health-care systems worldwide, but health systems are largely configured for individual diseases rather than multimorbidity. We examined the distribution of multimorbidity, and of comorbidity of physical and mental health disorders, in relation to age and socioeconomic deprivation.
METHODS: In a cross-sectional study we extracted data on 40 morbidities from a database of 1,751,841 people registered with 314 medical practices in Scotland as of March, 2007. We analysed the data according to the number of morbidities, disorder type (physical or mental), sex, age, and socioeconomic status. We defined multimorbidity as the presence of two or more disorders.
FINDINGS: 42·2% (95% CI 42·1-42·3) of all patients had one or more morbidities, and 23·2% (23·08-23·21) were multimorbid. Although the prevalence of multimorbidity increased substantially with age and was present in most people aged 65 years and older, the absolute number of people with multimorbidity was higher in those younger than 65 years (210,500 vs 194,996). Onset of multimorbidity occurred 10-15 years earlier in people living in the most deprived areas compared with the most affluent, with socioeconomic deprivation particularly associated with multimorbidity that included mental health disorders (prevalence of both physical and mental health disorder 11·0%, 95% CI 10·9-11·2% in most deprived area vs 5·9%, 5·8%-6·0% in least deprived). The presence of a mental health disorder increased as the number of physical morbidities increased (adjusted odds ratio 6·74, 95% CI 6·59-6·90 for five or more disorders vs 1·95, 1·93-1·98 for one disorder), and was much greater in more deprived than in less deprived people (2·28, 2·21-2·32 vs 1·08, 1·05-1·11).
INTERPRETATION: Our findings challenge the single-disease framework by which most health care, medical research, and medical education is configured. A complementary strategy is needed, supporting generalist clinicians to provide personalised, comprehensive continuity of care, especially in socioeconomically deprived areas. FUNDING: Scottish Government Chief Scientist Office.
Copyright © 2012 Elsevier Ltd. All rights reserved.

Entities:  

Mesh:

Year:  2012        PMID: 22579043     DOI: 10.1016/S0140-6736(12)60240-2

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  1830 in total

1.  Postnatal development of testicular capillaries and the effect of experimental cryptorchid on capillaries in rats.

Authors:  K Nakashima
Journal:  Jpn J Vet Res       Date:  1975-07       Impact factor: 0.649

2.  Understanding multimorbidity in primary health care.

Authors:  Kathryn Nicholson; Amanda L Terry; Martin Fortin; Tyler Williamson; Amardeep Thind
Journal:  Can Fam Physician       Date:  2015-10       Impact factor: 3.275

3.  Impact of Comorbidities and Age on Cause-Specific Mortality in Postmenopausal Patients with Breast Cancer.

Authors:  Marloes G M Derks; Cornelis J H van de Velde; Daniele Giardiello; Caroline Seynaeve; Hein Putter; Johan W R Nortier; Luc Y Dirix; Esther Bastiaannet; Johanneke E A Portielje; Gerrit-Jan Liefers
Journal:  Oncologist       Date:  2019-01-03

4.  NHS dental service utilisation and social deprivation in older adults in North West England.

Authors:  K W McKenzie; M Goodwin; I Pretty
Journal:  Br Dent J       Date:  2017-07-21       Impact factor: 1.626

5.  General Practitioners' Empathy and Health Outcomes: A Prospective Observational Study of Consultations in Areas of High and Low Deprivation.

Authors:  Stewart W Mercer; Maria Higgins; Annemieke M Bikker; Bridie Fitzpatrick; Alex McConnachie; Suzanne M Lloyd; Paul Little; Graham C M Watt
Journal:  Ann Fam Med       Date:  2016-03       Impact factor: 5.166

6.  Multimorbidity in patients attending 2 Australian primary care practices.

Authors:  Tom Brett; Diane Elizabeth Arnold-Reed; Aurora Popescu; Bishoy Soliman; Max Kishor Bulsara; Hilary Fine; Geoff Bovell; Robert George Moorhead
Journal:  Ann Fam Med       Date:  2013 Nov-Dec       Impact factor: 5.166

7.  Coexisting chronic conditions associated with mortality and morbidity in adult patients with asthma.

Authors:  Kaharu Sumino; Katiuscia O'Brian; Brian Bartle; David H Au; Mario Castro; Todd A Lee
Journal:  J Asthma       Date:  2014-01-27       Impact factor: 2.515

Review 8.  A practical approach to the pharmacological management of hypertension in older people.

Authors:  Nikesh Parekh; Amy Page; Khalid Ali; Kevin Davies; Chakravarthi Rajkumar
Journal:  Ther Adv Drug Saf       Date:  2016-12-27

9.  Participatory design of a preliminary safety checklist for general practice.

Authors:  Paul Bowie; Julie Ferguson; Marion MacLeod; Susan Kennedy; Carl de Wet; Duncan McNab; Moya Kelly; John McKay; Sarah Atkinson
Journal:  Br J Gen Pract       Date:  2015-05       Impact factor: 5.386

10.  Multiplicity of risk factors in ischemic stroke patients: relations to age, sex, and subtype--a study of 2,505 patients from the lund stroke register.

Authors:  Heléne Starby; Hossein Delavaran; Gunnar Andsberg; Håkan Lövkvist; Bo Norrving; Arne Lindgren
Journal:  Neuroepidemiology       Date:  2014-02-20       Impact factor: 3.282

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.