| Literature DB >> 28220336 |
Hikmet Budak1, Baohong Zhang2.
Abstract
Non-coding RNAs such as microRNAs (miRNAs) are very tiny ribonucleotides having an essential role in gene regulation at both post-transcriptional and translational levels. They are very conserved and expressed in worms, flies, plants, and mammals in a sequence-specific manner. Furthermore, it is now possible to clone miRNAs using the new genome editing tool CRISPR/cas9, which shows benefit in control of untargeted effect. In this special issue, we tried to cover researches associated with functional roles of miRNAs accross model and complex organisms.Keywords: CRISPR/Cas; Noncoding RNAs; Plant and human genome; miRNAs
Mesh:
Substances:
Year: 2017 PMID: 28220336 DOI: 10.1007/s10142-017-0544-1
Source DB: PubMed Journal: Funct Integr Genomics ISSN: 1438-793X Impact factor: 3.410