Literature DB >> 28217100

Corrigendum: Safety Profiles of Tripterygium wilfordii Hook F: A Systematic Review and Meta-Analysis.

Chi Zhang1, Ping-Ping Sun2, Hong-Tao Guo3, Yan Liu4, Jian Li2, Xiao-Juan He1, Ai-Ping Lu5.   

Abstract

[This corrects the article on p. 402 in vol. 7, PMID: 27877128.].

Entities:  

Keywords:  Tripterygium wilfordii Hook F; adverse event; meta-analysis; safety; systematic review

Year:  2017        PMID: 28217100      PMCID: PMC5309240          DOI: 10.3389/fphar.2017.00059

Source DB:  PubMed          Journal:  Front Pharmacol        ISSN: 1663-9812            Impact factor:   5.810


In the original article, there was an error. “Aspirin” was referred to instead of “TwHF.” A correction has been made to the last sentence of the Results section in the abstract: We screened 4137 abstracts for eligibility and included 594 studies in the analysis. The overall incidence of AEs was 26.7% (95% CI 24.8%, 28.8%) in 23,256 TwHF users. The estimates did vary markedly when stratified by specific study types. The incidence of gastrointestinal symptoms, adverse reproductive outcomes, adverse skin reactions, hematologic events and cardiovascular events were 13.3% (95% CI 11.9%, 14.9%), 11.7% (95% CI 10.3%, 13.3%), 7.8% (95% CI 6.3–9.5%), 6.5% (95% CI 5.7–7.4 %) and 4.9% (95% CI 1.6 %, 14.3 %), respectively. The prevalence of irregular menstruation (IM) was increased in patients taking TwHF compared with those given control (odds ratio [OR] 4.65, 95% CI 3.08 to 7.03). TwHF use has lower risk of weight gain (OR 0.12 [95% CI 0.04 to 0.39]) and hair loss (OR 0.37 [95% CI 0.18 to 0.78]). Furthermore, long-term TwHF use (>6 months) has a higher AEs incidence (31.0% [95% CI 24.5%–38.5%]). The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way.

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
  2 in total

Review 1.  Immunoregulatory effects of Tripterygium wilfordii Hook F and its extracts in clinical practice.

Authors:  Dan Luo; Zhengyun Zuo; Hongyan Zhao; Yong Tan; Cheng Xiao
Journal:  Front Med       Date:  2019-01-02       Impact factor: 4.592

Review 2.  The Effect of Triptolide in Rheumatoid Arthritis: From Basic Research towards Clinical Translation.

Authors:  Danping Fan; Qingqing Guo; Jiawen Shen; Kang Zheng; Cheng Lu; Ge Zhang; Aiping Lu; Xiaojuan He
Journal:  Int J Mol Sci       Date:  2018-01-26       Impact factor: 5.923

  2 in total

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