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Literature DB >> 2821491

Potential secondary and tertiary structure in the genomic RNA of foot and mouth disease virus.

B E Clarke¹, A L Brown, K M Currey, S E Newton, D J Rowlands, A R Carroll.

Abstract

The nucleotide sequence of the 5' untranslated region of foot and mouth disease virus (FMDV), serotype A10 has been determined. This completes the first total genomic sequence for any one serotype of FMDV. Analysis of the sequence to the 3' side of the poly (C) tract reveals the presence of a 24 nucleotide repeated motif which has homologies with a sequence located upstream of the transcriptional initiation site from several mammalian fibrinogen genes. The function of this element in FMDV is unclear. However, computer analysis of this region predicts the presence of a high degree of secondary and tertiary structure in which these repeats form an important part. The implications of these predictions are discussed.

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Year: 1987 PMID： 2821491 PMCID： PMC306193 DOI： 10.1093/nar/15.17.7067

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

30 in total

1. Insertion mutagenesis to increase secondary structure within the 5' noncoding region of a eukaryotic mRNA reduces translational efficiency.

Authors: J Pelletier; N Sonenberg
Journal: Cell Date: 1985-03 Impact factor: 41.582

2. Secondary structure of poliovirus RNA: correlation of computer-predicted with electron microscopically observed structure.

Authors: K M Currey; B M Peterlin; J V Maizel
Journal: Virology Date: 1986-01-15 Impact factor: 3.616

3. A new principle of RNA folding based on pseudoknotting.

Authors: C W Pleij; K Rietveld; L Bosch
Journal: Nucleic Acids Res Date: 1985-03-11 Impact factor: 16.971

4. Nucleotide and amino acid sequence coding for polypeptides of foot-and-mouth disease virus type A12.

Authors: B H Robertson; M J Grubman; G N Weddell; D M Moore; J D Welsh; T Fischer; D J Dowbenko; D G Yansura; B Small; D G Kleid
Journal: J Virol Date: 1985-06 Impact factor: 5.103

5. The sequence of foot-and-mouth disease virus RNA to the 5' side of the poly(C) tract.

Authors: S E Newton; A R Carroll; R O Campbell; B E Clarke; D J Rowlands
Journal: Gene Date: 1985 Impact factor: 3.688

6. Nucleotide sequence and genome organization of foot-and-mouth disease virus.

Authors: S Forss; K Strebel; E Beck; H Schaller
Journal: Nucleic Acids Res Date: 1984-08-24 Impact factor: 16.971

7. Photochemical cross-linking of cap binding proteins to eucaryotic mRNAs: effect of mRNA 5' secondary structure.

Authors: J Pelletier; N Sonenberg
Journal: Mol Cell Biol Date: 1985-11 Impact factor: 4.272

8. Analysis of the secondary structure of the poly(C) tract in foot-and-mouth disease virus RNAs.

Authors: E J Mellor; F Brown; T J Harris
Journal: J Gen Virol Date: 1985-09 Impact factor: 3.891

9. Two initiation sites for foot-and-mouth disease virus polyprotein in vivo.

Authors: B E Clarke; D V Sangar; J N Burroughs; S E Newton; A R Carroll; D J Rowlands
Journal: J Gen Virol Date: 1985-12 Impact factor: 3.891

10. Influences of mRNA secondary structure on initiation by eukaryotic ribosomes.

Authors: M Kozak
Journal: Proc Natl Acad Sci U S A Date: 1986-05 Impact factor: 11.205

35 in total

1. Conserved RNA secondary structures in Picornaviridae genomes.

Authors: C Witwer; S Rauscher; I L Hofacker; P F Stadler
Journal: Nucleic Acids Res Date: 2001-12-15 Impact factor: 16.971

2. Comparison and analysis of the complete nucleotide sequence of foot-and-mouth disease viruses from animals in Korea and other PanAsia strains.

Authors: Jae Ku Oem; Kwang Nyeong Lee; In Soo Cho; Soo Jeong Kye; Jong Hyeon Park; Yi Seok Joo
Journal: Virus Genes Date: 2004-08 Impact factor: 2.332

3. NMR solution structure of poliovirus uridylyated peptide linked to the genome (VPgpU).

Authors: Catherine H Schein; Numan Oezguen; Gerbrand J van der Heden van Noort; Dmitri V Filippov; Aniko Paul; Eric Kumar; Werner Braun
Journal: Peptides Date: 2010-05-02 Impact factor: 3.750

4. Prediction of RNA secondary structure, including pseudoknotting, by computer simulation.

Authors: J P Abrahams; M van den Berg; E van Batenburg; C Pleij
Journal: Nucleic Acids Res Date: 1990-05-25 Impact factor: 16.971

5. The computer simulation of RNA folding involving pseudoknot formation.

Authors: A P Gultyaev
Journal: Nucleic Acids Res Date: 1991-05-11 Impact factor: 16.971

6. Comparative analysis of the large fragment of the 5' untranslated region (LF-5' UTR) of serotype A foot-and-mouth disease virus field isolates from India.

Authors: Jajati K Mohapatra; Abhipsa Sahu; Sushanta K Barik; Aniket Sanyal; Bramhadev Pattnaik
Journal: Virus Genes Date: 2009-05-15 Impact factor: 2.332

10. Identification and characterization of a cis-acting replication element (cre) adjacent to the internal ribosome entry site of foot-and-mouth disease virus.

Authors: Peter W Mason; Svetlana V Bezborodova; Tina M Henry
Journal: J Virol Date: 2002-10 Impact factor: 5.103