| Literature DB >> 28211300 |
Prawez Alam1, Mohammad J Ansari2, Md Khalid Anwer2, Mohammad Raish3, Yoonus K T Kamal1, Faiyaz Shakeel4.
Abstract
The aim of this study was to investigate the wound healing effects of clove oil (CO) via its encapsulation into nanoemulsion. Optimized nanoemulsion (droplet size of 29.10 nm) was selected for wound healing investigation, collagen determination, and histopathological examination in rats. Optimized nanoemulsion presented significant would healing effects in rats as compared to pure CO. Nanoemulsion also presented significant enhancement in leucine content (0.61 mg/g) as compared to pure CO (0.50 mg/g) and negative control (0.31 mg/g). Histopathology of nanoemulsion treated rats showed no signs of inflammatory cells. These results suggested that nanoemulsion of CO was safe and nontoxic.Entities:
Keywords: Clove oil; collagen; histopathology; leucine; nanoemulsion; wound healing
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Year: 2016 PMID: 28211300 DOI: 10.3109/21691401.2016.1163716
Source DB: PubMed Journal: Artif Cells Nanomed Biotechnol ISSN: 2169-1401 Impact factor: 5.678