| Literature DB >> 28211085 |
Jeff Goldsmith1, Joseph E Schwartz2,3.
Abstract
We propose methods for variable selection in the context of modeling the association between a functional response and concurrently observed functional predictors. This data structure, and the need for such methods, is exemplified by our motivating example: a study in which blood pressure values are observed throughout the day, together with measurements of physical activity, location, posture, affect or mood, and other quantities that may influence blood pressure. We estimate the coefficients of the concurrent functional linear model using variational Bayes and jointly model residual correlation using functional principal components analysis. Latent binary indicators partition coefficient functions into included and excluded sets, incorporating variable selection into the estimation framework. The proposed methods are evaluated in simulations and real-data analyses, and are implemented in a publicly available R package with supporting interactive graphics for visualization.Entities:
Keywords: ambulatory blood pressure; functional data; intensive longitudinal data; spline smoothing; variational Bayes; wearable devices
Mesh:
Year: 2017 PMID: 28211085 PMCID: PMC5457356 DOI: 10.1002/sim.7254
Source DB: PubMed Journal: Stat Med ISSN: 0277-6715 Impact factor: 2.373