Literature DB >> 2820558

Demonstration of 1,25(OH)2 vitamin D3 receptors and actions in vascular smooth muscle cells in vitro.

J Merke1, W Hofmann, D Goldschmidt, E Ritz.   

Abstract

Binding of [3H] 1,25(OH)2D3 and effects of 1,25(OH)2D3 on cell ultrastructure were evaluated in vascular smooth muscle cells (VSMC) primary cultures (aortic media). Specific reversible binding of [3H] 1,25(OH)2D3 by a 3.5 S macromolecule with DNA binding, KD 6.2 X 10(-10) M and Nmax 16 fmol/mg protein was demonstrated. Incubation of VSMC with 10(-8) M 1,25(OH)2D3, but not 25(OH)D3, in the presence of 10% FCS for up to three weeks caused rapid reversible appearance in the cytoplasm of membrane-bounded electron-dense lysosomal particles which on electronspectroscopic imaging contained Ca and Pi. VSMC are targets for vitamin D.

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Year:  1987        PMID： 2820558     DOI： 10.1007/BF02555253

Source DB:  PubMed          Journal:  Calcif Tissue Int        ISSN： 0171-967X            Impact factor:   4.333


  7 in total

1.  Presence of a 1,25-dihydroxy-vitamin D3 receptor in chick skeletal muscle myoblasts.

Authors:  R Boland; A Norman; E Ritz; W Hasselbach
Journal:  Biochem Biophys Res Commun       Date:  1985-04-16       Impact factor: 3.575

2.  No 1,25-dihydroxyvitamin D3 receptors on osteoclasts of calcium-deficient chicken despite demonstrable receptors on circulating monocytes.

Authors:  J Merke; G Klaus; U Hügel; R Waldherr; E Ritz
Journal:  J Clin Invest       Date:  1986-01       Impact factor: 14.808

3.  1,25-Dihydroxyvitamin D3 receptors identified in the rat heart.

Authors:  M R Walters; D C Wicker; P C Riggle
Journal:  J Mol Cell Cardiol       Date:  1986-01       Impact factor: 5.000

4.  Experimental arteriosclerosis in Rhesus monkeys induced by multiple risk factors: cholesterol, vitamin D, and nictotine.

Authors:  L B Liu; C B Taylor; S K Peng; B Mikkelson
Journal:  Paroi Arterielle       Date:  1979-04

5.  Identification of 1,25-dihydroxyvitamin D3 receptors and activities in muscle.

Authors:  R U Simpson; G A Thomas; A J Arnold
Journal:  J Biol Chem       Date:  1985-07-25       Impact factor: 5.157

6.  Abnormal vitamin D metabolism, intestinal calcium transport, and bone calcium status in the spontaneously hypertensive rat compared with its genetic control.

Authors:  P A Lucas; R C Brown; T Drüeke; B Lacour; J A Metz; D A McCarron
Journal:  J Clin Invest       Date:  1986-07       Impact factor: 14.808

7.  The smooth muscle cell. II. Growth of smooth muscle in culture and formation of elastic fibers.

Authors:  R Ross
Journal:  J Cell Biol       Date:  1971-07       Impact factor: 10.539
  7 in total
  31 in total

1.  Meta-Analysis of the Association Between the rs228570 Vitamin D Receptor Gene Polymorphism and Arterial Hypertension Risk.

Authors:  Ivone F O C Nunes; Ana A C M Cavalcante; Marcus V O B Alencar; Marcos D F Carvalho; José L R Sarmento; Nayra S C C A Teixeira; Adriana A Paiva; Lídia R Carvalho; Leopoldo F M Nascimento; Maria S P Cruz; Marcelo M Rogero; Andréia C B Lima; Cecilia M R G Carvalho
Journal:  Adv Nutr       Date:  2020-09-01       Impact factor: 8.701

Review 2.  The dualistic role of vitamin D in vascular calcifications.

Authors:  M Shawkat Razzaque
Journal:  Kidney Int       Date:  2010-10-20       Impact factor: 10.612

3.  1,25-dihydroxyvitamin D3 modulates growth of vascular smooth muscle cells.

Authors:  T Mitsuhashi; R C Morris; H E Ives
Journal:  J Clin Invest       Date:  1991-06       Impact factor: 14.808

4.  Association of vitamin D status and blood pressure response after renal denervation.

Authors:  Janine Pöss; Felix Mahfoud; Christian Ukena; Murray David Esler; Markus Schlaich; Dagmara Hering; Bodo Cremers; Ulrich Laufs; Michael Böhm
Journal:  Clin Res Cardiol       Date:  2013-10-31       Impact factor: 5.460

Review 5.  Vitamin D and cardiovascular disease: potential role in health disparities.

Authors:  Jorge N Artaza; Sandra Contreras; Leah A Garcia; Rajnish Mehrotra; Gary Gibbons; Ralph Shohet; David Martins; Keith C Norris
Journal:  J Health Care Poor Underserved       Date:  2011

6.  Vitamin D status and coronary flow reserve measured by positron emission tomography: a co-twin control study.

Authors:  Cristina Karohl; Viola Vaccarino; Emir Veledar; Jack Goldberg; Vin Tangpricha; Antonio Bellasi; Paolo Raggi
Journal:  J Clin Endocrinol Metab       Date:  2012-11-08       Impact factor: 5.958

7.  The effect of vitamin D treatment on decreased levels of ATP and energy charge in the thoracic aorta of uraemic rats.

Authors:  M Krog; S Ejerblad; H Johansson; G Ronquist
Journal:  Br J Exp Pathol       Date:  1989-04

Review 8.  Vitamin D deficiency in the pathogenesis of hypertension: still an unsettled question.

Authors:  Stephen G Rostand
Journal:  Curr Hypertens Rep       Date:  2014-08       Impact factor: 5.369

9.  Calcium and vitamin D intakes may be positively associated with brain lesions in depressed and nondepressed elders.

Authors:  Martha E Payne; John J B Anderson; David C Steffens
Journal:  Nutr Res       Date:  2008-05       Impact factor: 3.315

Review 10.  Vitamin D in patients with chronic kidney disease: a position statement of the Working Group "Trace Elements and Mineral Metabolism" of the Italian Society of Nephrology.

Authors:  Luigi Francesco Morrone; Pergiorgio Bolasco; Corrado Camerini; Giuseppe Cianciolo; Adamasco Cupisti; Andrea Galassi; Sandro Mazzaferro; Domenico Russo; Luigi Russo; Mario Cozzolino
Journal:  J Nephrol       Date:  2016-04-09       Impact factor: 3.902
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