Literature DB >> 28205336

Achieving serum urate targets in gout: an audit in a gout-oriented rheumatology practice.

Elizabeth J M Corbett1, Peta Pentony2, Neil W McGill1,3.   

Abstract

AIM: To assess the proportion of patients with gout who achieve target serum urate levels, the drug regime required and the reasons for failing to do so.
METHODS: We reviewed the files of all patients with gout who presented to a gout-oriented rheumatology practice between January 2010 and September 2014.
RESULTS: Two hundred and thirty patients agreed to commence urate lowering therapy (ULT); 73% achieved their urate target, including 74% with non-tophaceous gout (target ≤ 0.36 mmol/L) and 71% with tophi (target ≤ 0.30 mmol/L). Of the 62 who failed to reach target, in 61 it was due to non-adherence and in one due to inefficacy.
CONCLUSION: Adherence remains the major challenge to successful long-term gout management.
© 2017 Asia Pacific League of Associations for Rheumatology and John Wiley & Sons Australia, Ltd.

Entities:  

Keywords:  adherence; gout; urate

Mesh:

Substances:

Year:  2017        PMID: 28205336     DOI: 10.1111/1756-185X.13032

Source DB:  PubMed          Journal:  Int J Rheum Dis        ISSN: 1756-1841            Impact factor:   2.454


  3 in total

1.  Improvement in OMERACT domains and renal function with regular treatment for gout: a 12-month follow-up cohort study.

Authors:  Janitzia Vazquez-Mellado; Ingris Peláez-Ballestas; Rubén Burgos-Vargas; Everardo Alvarez-Hernández; Sergio García-Méndez; Virginia Pascual-Ramos; Marina Rull-Gabayet
Journal:  Clin Rheumatol       Date:  2018-03-15       Impact factor: 2.980

2.  Rate of adherence to urate-lowering therapy among patients with gout: a systematic review and meta-analysis.

Authors:  Rulan Yin; Lin Li; Guo Zhang; Yafei Cui; Lijuan Zhang; Qiuxiang Zhang; Ting Fu; Haixia Cao; Liren Li; Zhifeng Gu
Journal:  BMJ Open       Date:  2018-04-10       Impact factor: 2.692

Review 3.  Improving adherence to gout therapy: an expert review.

Authors:  Fernando Perez-Ruiz; Giovambattista Desideri
Journal:  Ther Clin Risk Manag       Date:  2018-05-03       Impact factor: 2.423

  3 in total

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