Tomáš Franěk1, Karel Kotaška1, Richard Průša1. 1. Department of Medical Chemistry and Clinical Biochemistry 2nd Faculty of Medicine, Faculty Hospital Motol, Charles University, Prague, Czech Republic.
Abstract
BACKGROUND: The homeostasis of essential trace elements such as selenium and manganese may be altered in patients with severe diseases of various etiologies (trauma brain injuries, tumors, leukemias, lymphomas, neurological diseases). METHODS: Concentration of manganese and selenium were determined in cerebrospinal fluid by electrothermal atomic absorption spectrometry in 50 hospitalized children with various clinical ethiologies including oncological, neurological, and brain related diseases. RESULTS: The concentrations of manganese in cerebrospinal fluid of children were 0.97±0.67 μg/L. The concentrations of selenium were 13.3±3.5 μg/L. The concentrations were similar as published in adults. The values did not correlated with the age, gender and severity of the disease. CONCLUSION: We evaluated values of selenium and manganese in cerebrospinal fluid of seriously diseased children.
BACKGROUND: The homeostasis of essential trace elements such as selenium and manganese may be altered in patients with severe diseases of various etiologies (trauma brain injuries, tumors, leukemias, lymphomas, neurological diseases). METHODS: Concentration of manganese and selenium were determined in cerebrospinal fluid by electrothermal atomic absorption spectrometry in 50 hospitalized children with various clinical ethiologies including oncological, neurological, and brain related diseases. RESULTS: The concentrations of manganese in cerebrospinal fluid of children were 0.97±0.67 μg/L. The concentrations of selenium were 13.3±3.5 μg/L. The concentrations were similar as published in adults. The values did not correlated with the age, gender and severity of the disease. CONCLUSION: We evaluated values of selenium and manganese in cerebrospinal fluid of seriously diseased children.
Authors: G Forte; B Bocca; O Senofonte; F Petrucci; L Brusa; P Stanzione; S Zannino; N Violante; A Alimonti; G Sancesario Journal: J Neural Transm (Vienna) Date: 2004-03-19 Impact factor: 3.575
Authors: M V Aguilar; F J Jiménez-Jiménez; J A Molina; I Meseguer; C J Mateos-Vega; M J González-Muñoz; F de Bustos; C Gómez-Escalonilla; M Ort-Pareja; M Zurdo; M C Martínez-Para Journal: J Neural Transm (Vienna) Date: 1998 Impact factor: 3.575