Literature DB >> 2820139

Expression of a cDNA clone corresponding to the long open reading frame (XBL-I) of the bovine leukemia virus.

L Willems, C Bruck, D Portetelle, A Burny, R Kettmann.   

Abstract

Nucleotide sequence analysis of a cDNA clone corresponding to the XBL-I open reading-frame of bovine leukemia virus (BLV) revealed that the AUG initiation codon was located 44 bases downstream from that of the env gene and was part of the p34x mRNA splice donor. . .ATGG/GTAA at the end of the pol gene sequence. RNA from this clone was synthesized in vitro by the SP6 RNA polymerase and translated into a 34,000 mol wt protein in rabbit reticulocyte lysates. The protein (p34x) is recognized in Western blots by most sera of BLV-infected sheep and tumor-bearing cattle, by an anti-synthetic peptide rabbit serum, and by the serum of a rabbit immunized by XBL-I RNA programmed reticulocyte lysates. Both sera react with a 34,000 mol wt protein present in nuclei of BLV-infected cells.

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Year:  1987        PMID： 2820139     DOI： 10.1016/0042-6822(87)90043-2

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


  7 in total

1.  Even transcriptionally competent proviruses are silent in bovine leukemia virus-induced sheep tumor cells.

Authors:  A Van den Broeke; Y Cleuter; G Chen; D Portetelle; M Mammerickx; D Zagury; M Fouchard; L Coulombel; R Kettmann; A Burny
Journal:  Proc Natl Acad Sci U S A       Date:  1988-12       Impact factor: 11.205

2.  In vivo leukocyte tropism of bovine leukemia virus in sheep and cattle.

Authors:  I Schwartz; A Bensaid; B Polack; B Perrin; M Berthelemy; D Levy
Journal:  J Virol       Date:  1994-07       Impact factor: 5.103

3.  Episodic occurrence of antibodies against the bovine leukemia virus Rex protein during the course of infection in sheep.

Authors:  M A Powers; D Grossman; L C Kidd; K Radke
Journal:  J Virol       Date:  1991-09       Impact factor: 5.103

4.  Identification of alternatively spliced mRNAs encoding potential new regulatory proteins in cattle infected with bovine leukemia virus.

Authors:  S Alexandersen; S Carpenter; J Christensen; T Storgaard; B Viuff; Y Wannemuehler; J Belousov; J A Roth
Journal:  J Virol       Date:  1993-01       Impact factor: 5.103

5.  Fusogenic segments of bovine leukemia virus and simian immunodeficiency virus are interchangeable and mediate fusion by means of oblique insertion in the lipid bilayer of their target cells.

Authors:  V Vonèche; D Portetelle; R Kettmann; L Willems; K Limbach; E Paoletti; J M Ruysschaert; A Burny; R Brasseur
Journal:  Proc Natl Acad Sci U S A       Date:  1992-05-01       Impact factor: 11.205

6.  Cooperation between bovine leukaemia virus transactivator protein and Ha-ras oncogene product in cellular transformation.

Authors:  L Willems; H Heremans; G Chen; D Portetelle; A Billiau; A Burny; R Kettmann
Journal:  EMBO J       Date:  1990-05       Impact factor: 11.598

Review 7.  Mechanisms of leukemogenesis induced by bovine leukemia virus: prospects for novel anti-retroviral therapies in human.

Authors:  Nicolas Gillet; Arnaud Florins; Mathieu Boxus; Catherine Burteau; Annamaria Nigro; Fabian Vandermeers; Hervé Balon; Amel-Baya Bouzar; Julien Defoiche; Arsène Burny; Michal Reichert; Richard Kettmann; Luc Willems
Journal:  Retrovirology       Date:  2007-03-16       Impact factor: 4.602
  7 in total

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