Elisabeth Coupez1, Charles Merlin2, Viateur Tuyisenge3, Laurent Sarry3, Bruno Pereira4, Jean René Lusson5, Louis Boyer6, Lucie Cassagnes6. 1. Department of Cardiology, CHU Gabriel Montpied, Clermont-Ferrand, France. ecoupez@chu-clermontferrand.fr. 2. Nuclear Medicine Department, Jean Perrin Cancer Center, Clermont-Ferrand, France. 3. ISIT, UMR CNRS 6284, Université d'Auvergne Clermont1, Clermont-Ferrand, France. 4. DRCI, CHU Gabriel Montpied, Clermont-Ferrand, France. 5. Department of Cardiology, CHU Gabriel Montpied, Clermont-Ferrand, France. 6. Department of Radiology, CHU Gabriel Montpied, Clermont-Ferrand, France.
Abstract
BACKGROUND: There are paucity of data comparing measurements of left ventricular systolic performance using cadmium-zinc-telluride (CZT) semiconductor cameras with other imaging modalities. This study compared the new system with echocardiography (echo) and cardiac magnetic resonance (CMR) imaging. METHODS: 60 Patients presenting with ST-elevated myocardial infarction (MI) were included. Each patient underwent echo, myocardial perfusion imaging using Spectrum Dynamics D-SPECT(r) (CZT-SPECT), and CMR 6 weeks after MI. The primary endpoint was the agreement between CZT-SPECT and CMR for left ventricular ejection fraction (LVEF) measurement. RESULTS: 48 of the 60 patients underwent all 3 studies (echo, CMR, and CZT-SPECT) 40 days after admission. CZT-SPECT and CMR LVEF were well correlated (r = .79, P < .0001), as well as CZT-SPECT vs echo and CMR vs echo (r = .79 and .84, respectively, P < .0001). The segmental LV wall thickening and wall motion also showed good concordance between three techniques. CONCLUSIONS: CZT-SPECT is reliable for LVEF measurement.
BACKGROUND: There are paucity of data comparing measurements of left ventricular systolic performance using cadmium-zinc-telluride (CZT) semiconductor cameras with other imaging modalities. This study compared the new system with echocardiography (echo) and cardiac magnetic resonance (CMR) imaging. METHODS: 60 Patients presenting with ST-elevated myocardial infarction (MI) were included. Each patient underwent echo, myocardial perfusion imaging using Spectrum Dynamics D-SPECT(r) (CZT-SPECT), and CMR 6 weeks after MI. The primary endpoint was the agreement between CZT-SPECT and CMR for left ventricular ejection fraction (LVEF) measurement. RESULTS: 48 of the 60 patients underwent all 3 studies (echo, CMR, and CZT-SPECT) 40 days after admission. CZT-SPECT and CMR LVEF were well correlated (r = .79, P < .0001), as well as CZT-SPECT vs echo and CMR vs echo (r = .79 and .84, respectively, P < .0001). The segmental LV wall thickening and wall motion also showed good concordance between three techniques. CONCLUSIONS:CZT-SPECT is reliable for LVEF measurement.
Entities:
Keywords:
Echocardiography; SPECT; left ventricular function; magnetic resonance imaging; myocardial infarction; myocardial perfusion imaging
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