Literature DB >> 28187278

Translating Germline Cancer Risk into Precision Prevention.

Matthew B Yurgelun1, Georgia Chenevix-Trench2, Scott M Lippman3.   

Abstract

Study of the biology of tumors caused by germline mutations has led to recent paradigm-changing therapy and is driving precision prevention efforts, including immune oncology and early detection research. Here, we explore recent biologic advances that are redefining the spectrum of cancers linked to various hereditary predisposition syndromes and can be leveraged to improve personalized risk assessment and develop novel interventions to prevent or intercept cancer.
Copyright © 2017 Elsevier Inc. All rights reserved.

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Year:  2017        PMID： 28187278     DOI： 10.1016/j.cell.2017.01.031

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   66.850


  7 in total

Review 1.  Future cancer research priorities in the USA: a Lancet Oncology Commission.

Authors:  Elizabeth M Jaffee; Chi Van Dang; David B Agus; Brian M Alexander; Kenneth C Anderson; Alan Ashworth; Anna D Barker; Roshan Bastani; Sangeeta Bhatia; Jeffrey A Bluestone; Otis Brawley; Atul J Butte; Daniel G Coit; Nancy E Davidson; Mark Davis; Ronald A DePinho; Robert B Diasio; Giulio Draetta; A Lindsay Frazier; Andrew Futreal; Sam S Gambhir; Patricia A Ganz; Levi Garraway; Stanton Gerson; Sumit Gupta; James Heath; Ruth I Hoffman; Cliff Hudis; Chanita Hughes-Halbert; Ramy Ibrahim; Hossein Jadvar; Brian Kavanagh; Rick Kittles; Quynh-Thu Le; Scott M Lippman; David Mankoff; Elaine R Mardis; Deborah K Mayer; Kelly McMasters; Neal J Meropol; Beverly Mitchell; Peter Naredi; Dean Ornish; Timothy M Pawlik; Jeffrey Peppercorn; Martin G Pomper; Derek Raghavan; Christine Ritchie; Sally W Schwarz; Richard Sullivan; Richard Wahl; Jedd D Wolchok; Sandra L Wong; Alfred Yung
Journal:  Lancet Oncol       Date:  2017-10-31       Impact factor: 41.316

2.  Polygenic Determinants for Subsequent Breast Cancer Risk in Survivors of Childhood Cancer: The St Jude Lifetime Cohort Study (SJLIFE).

Authors:  Zhaoming Wang; Jinghui Zhang; Yutaka Yasui; Leslie L Robison; Qi Liu; Carmen L Wilson; John Easton; Heather Mulder; Ti-Cheng Chang; Michael C Rusch; Michael N Edmonson; Stephen V Rice; Matthew J Ehrhardt; Rebecca M Howell; Chimene A Kesserwan; Gang Wu; Kim E Nichols; James R Downing; Melissa M Hudson
Journal:  Clin Cancer Res       Date:  2018-10-26       Impact factor: 12.531

Review 3.  Cancer genetics, precision prevention and a call to action.

Authors:  Clare Turnbull; Amit Sud; Richard S Houlston
Journal:  Nat Genet       Date:  2018-08-29       Impact factor: 38.330

4.  Precancer Atlas to Drive Precision Prevention Trials.

Authors:  Avrum Spira; Matthew B Yurgelun; Ludmil Alexandrov; Anjana Rao; Rafael Bejar; Kornelia Polyak; Marios Giannakis; Ali Shilatifard; Olivera J Finn; Madhav Dhodapkar; Neil E Kay; Esteban Braggio; Eduardo Vilar; Sarah A Mazzilli; Timothy R Rebbeck; Judy E Garber; Victor E Velculescu; Mary L Disis; Douglas C Wallace; Scott M Lippman
Journal:  Cancer Res       Date:  2017-04-01       Impact factor: 13.312

5.  The Role of the Microbiome in Cancer and the Development of Cancer Therapeutics.

Authors:  Kaitlyn C Belknap; Andrea L Cote; Colin M McGill; Cheryl P Andam; Brian M Barth
Journal:  Int J Biopharm Sci       Date:  2020-09-05

Review 6.  The paradox of cancer genes in non-malignant conditions: implications for precision medicine.

Authors:  Jacob J Adashek; Shumei Kato; Scott M Lippman; Razelle Kurzrock
Journal:  Genome Med       Date:  2020-02-17       Impact factor: 11.117

7.  GA4GH: International policies and standards for data sharing across genomic research and healthcare.

Authors:  Heidi L Rehm; Angela J H Page; Lindsay Smith; Jeremy B Adams; Gil Alterovitz; Lawrence J Babb; Maxmillian P Barkley; Michael Baudis; Michael J S Beauvais; Tim Beck; Jacques S Beckmann; Sergi Beltran; David Bernick; Alexander Bernier; James K Bonfield; Tiffany F Boughtwood; Guillaume Bourque; Sarion R Bowers; Anthony J Brookes; Michael Brudno; Matthew H Brush; David Bujold; Tony Burdett; Orion J Buske; Moran N Cabili; Daniel L Cameron; Robert J Carroll; Esmeralda Casas-Silva; Debyani Chakravarty; Bimal P Chaudhari; Shu Hui Chen; J Michael Cherry; Justina Chung; Melissa Cline; Hayley L Clissold; Robert M Cook-Deegan; Mélanie Courtot; Fiona Cunningham; Miro Cupak; Robert M Davies; Danielle Denisko; Megan J Doerr; Lena I Dolman; Edward S Dove; L Jonathan Dursi; Stephanie O M Dyke; James A Eddy; Karen Eilbeck; Kyle P Ellrott; Susan Fairley; Khalid A Fakhro; Helen V Firth; Michael S Fitzsimons; Marc Fiume; Paul Flicek; Ian M Fore; Mallory A Freeberg; Robert R Freimuth; Lauren A Fromont; Jonathan Fuerth; Clara L Gaff; Weiniu Gan; Elena M Ghanaim; David Glazer; Robert C Green; Malachi Griffith; Obi L Griffith; Robert L Grossman; Tudor Groza; Jaime M Guidry Auvil; Roderic Guigó; Dipayan Gupta; Melissa A Haendel; Ada Hamosh; David P Hansen; Reece K Hart; Dean Mitchell Hartley; David Haussler; Rachele M Hendricks-Sturrup; Calvin W L Ho; Ashley E Hobb; Michael M Hoffman; Oliver M Hofmann; Petr Holub; Jacob Shujui Hsu; Jean-Pierre Hubaux; Sarah E Hunt; Ammar Husami; Julius O Jacobsen; Saumya S Jamuar; Elizabeth L Janes; Francis Jeanson; Aina Jené; Amber L Johns; Yann Joly; Steven J M Jones; Alexander Kanitz; Kazuto Kato; Thomas M Keane; Kristina Kekesi-Lafrance; Jerome Kelleher; Giselle Kerry; Seik-Soon Khor; Bartha M Knoppers; Melissa A Konopko; Kenjiro Kosaki; Martin Kuba; Jonathan Lawson; Rasko Leinonen; Stephanie Li; Michael F Lin; Mikael Linden; Xianglin Liu; Isuru Udara Liyanage; Javier Lopez; Anneke M Lucassen; Michael Lukowski; Alice L Mann; John Marshall; Michele Mattioni; Alejandro Metke-Jimenez; Anna Middleton; Richard J Milne; Fruzsina Molnár-Gábor; Nicola Mulder; Monica C Munoz-Torres; Rishi Nag; Hidewaki Nakagawa; Jamal Nasir; Arcadi Navarro; Tristan H Nelson; Ania Niewielska; Amy Nisselle; Jeffrey Niu; Tommi H Nyrönen; Brian D O'Connor; Sabine Oesterle; Soichi Ogishima; Vivian Ota Wang; Laura A D Paglione; Emilio Palumbo; Helen E Parkinson; Anthony A Philippakis; Angel D Pizarro; Andreas Prlic; Jordi Rambla; Augusto Rendon; Renee A Rider; Peter N Robinson; Kurt W Rodarmer; Laura Lyman Rodriguez; Alan F Rubin; Manuel Rueda; Gregory A Rushton; Rosalyn S Ryan; Gary I Saunders; Helen Schuilenburg; Torsten Schwede; Serena Scollen; Alexander Senf; Nathan C Sheffield; Neerjah Skantharajah; Albert V Smith; Heidi J Sofia; Dylan Spalding; Amanda B Spurdle; Zornitza Stark; Lincoln D Stein; Makoto Suematsu; Patrick Tan; Jonathan A Tedds; Alastair A Thomson; Adrian Thorogood; Timothy L Tickle; Katsushi Tokunaga; Juha Törnroos; David Torrents; Sean Upchurch; Alfonso Valencia; Roman Valls Guimera; Jessica Vamathevan; Susheel Varma; Danya F Vears; Coby Viner; Craig Voisin; Alex H Wagner; Susan E Wallace; Brian P Walsh; Marc S Williams; Eva C Winkler; Barbara J Wold; Grant M Wood; J Patrick Woolley; Chisato Yamasaki; Andrew D Yates; Christina K Yung; Lyndon J Zass; Ksenia Zaytseva; Junjun Zhang; Peter Goodhand; Kathryn North; Ewan Birney
Journal:  Cell Genom       Date:  2021-11-10
  7 in total

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