| Literature DB >> 28179283 |
Hind Rafei1, Ehab El-Bahesh2, Antoine Finianos3, Samah Nassereddine1, Imad Tabbara4.
Abstract
Lung cancer is the leading cause of cancer-related death worldwide. Treatment of non-small cell lung cancer has evolved tremendously over the past decade. Specifically, immune checkpoint inhibitors have become an increasingly interesting target of pharmacological blockade. These immune inhibitors have shown promising results in front-line therapy and after failure of multiple lines, as well as in monotherapy and combination with other therapies. Vaccination in non-small cell lung cancer is also an emerging field of research that holds promising results for the future of immunotherapy in non-small cell lung cancer. This review presents a concise update on the most recent data regarding the role of checkpoint inhibitors as well as vaccination in non-small cell lung cancer. CopyrightEntities:
Keywords: Non-small cell lung cancer; checkpoint inhibitors; immunotherapy; review; vaccine
Mesh:
Year: 2017 PMID: 28179283 DOI: 10.21873/anticanres.11330
Source DB: PubMed Journal: Anticancer Res ISSN: 0250-7005 Impact factor: 2.480