Literature DB >> 35836900

Efficacy and safety of thoracoscopic resection for early-stage non-small cell lung cancer.

Peng Cao1, Jiaqi Yue1, Shan Hu1, Kangle Kong1, Peng Han1, Ziheng Yang1, Yu Deng1, Fan Li1, Bo Zhao1.   

Abstract

OBJECTIVE: To explore the efficacy and safety of thoracoscopic resection for early-stage non-small cell lung cancer (NSCLC).
METHODS: A total of 110 patients with early-stage NSCLC admitted to Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology between August 2017 and December 2019 were enrolled and retrospectively analysed. Among them, 60 patients receiving thoracoscopic resection for lung cancer (LC) were assigned to the research group (Res group) and another 50 patients treated with routine open radical resection for LC were included in the control group (Con group). The following items of the two groups were evaluated and compared: treatment efficacy, operation indexes, VAS score, lung function, lung capacity, complications, 2-year tumour-free survival rate, 2-year survival rate, and quality of life (QoL).
RESULTS: The Res group showed significantly better efficacy, and lower incidence of complications and VAS score than the Con group. In addition, patients in the Res group experienced less intraoperative blood loss, earlier anal exhaust, shorter hospital stay and indwelling time of drainage tube as well as less drainage volume. Furthermore, better recovery in pulmonary function and lung capacity, and significantly higher 2-year tumour-free survival rate, 2-year survival rate as well as postoperative QoL were noted in the Res group compared with the Con group.
CONCLUSION: Thoracoscopic resection for LC is effective in the treatment of patients with early-stage NSCLC. It can substantially shorten the hospital stay and indwelling time of drainage tube and reduce drainage volume and blood loss, with high safety. AJTR
Copyright © 2022.

Entities:  

Keywords:  Thoracoscopic resection for lung cancer; early-stage non-small cell lung cancer; efficacy; safety

Year:  2022        PMID: 35836900      PMCID: PMC9274577     

Source DB:  PubMed          Journal:  Am J Transl Res        ISSN: 1943-8141            Impact factor:   3.940


  27 in total

1.  Initial results of pulmonary resection after neoadjuvant nivolumab in patients with resectable non-small cell lung cancer.

Authors:  Matthew J Bott; Stephen C Yang; Bernard J Park; Prasad S Adusumilli; Valerie W Rusch; James M Isbell; Robert J Downey; Julie R Brahmer; Richard Battafarano; Errol Bush; Jamie Chaft; Patrick M Forde; David R Jones; Stephen R Broderick
Journal:  J Thorac Cardiovasc Surg       Date:  2018-12-13       Impact factor: 5.209

Review 2.  Are segmentectomy and lobectomy comparable in terms of curative intent for early stage non-small cell lung cancer?

Authors:  Takahiro Mimae; Morihito Okada
Journal:  Gen Thorac Cardiovasc Surg       Date:  2019-11-06

Review 3.  Advances in the Treatment of Non-Small Cell Lung Cancer: Immunotherapy.

Authors:  Shetal A Patel; Jared Weiss
Journal:  Clin Chest Med       Date:  2020-04-16       Impact factor: 2.878

Review 4.  Systemic Therapy for Locally Advanced and Metastatic Non-Small Cell Lung Cancer: A Review.

Authors:  Kathryn C Arbour; Gregory J Riely
Journal:  JAMA       Date:  2019-08-27       Impact factor: 56.272

Review 5.  Limited resection for early-stage non-small cell lung cancer as function-preserving radical surgery: a review.

Authors:  Keiju Aokage; Junji Yoshida; Tomoyuki Hishida; Masahiro Tsuboi; Hisashi Saji; Morihito Okada; Kenji Suzuki; Syunichi Watanabe; Hisao Asamura
Journal:  Jpn J Clin Oncol       Date:  2016-10-20       Impact factor: 3.019

6.  Outcome and Safety of Radical Resection in Non-Small Cell Lung Cancer Patients via Glasses-Free 3-Dimensional Video-Assisted Thoracoscope Versus 2-Dimensional Video-Assisted Thoracoscope.

Authors:  Weizhe Huang; Jun Liu; Wenhua Liang; Wenlong Shao; Zhibin Lan; Long Jiang; Lili Mo; Diego Gonzalez-Rivas; Jianxing He
Journal:  Surg Innov       Date:  2018-01-22       Impact factor: 2.058

Review 7.  Molecular therapeutic targets in non-small cell lung cancer.

Authors:  Kamya Sankar; Shirish M Gadgeel; Angel Qin
Journal:  Expert Rev Anticancer Ther       Date:  2020-07-07       Impact factor: 4.512

8.  Molecular diagnostics and targeted therapies in non-small cell lung cancer (NSCLC): an update.

Authors:  Sushma Jonna; Deepa S Subramaniam
Journal:  Discov Med       Date:  2019-03       Impact factor: 2.970

9.  Fast-track surgery in single-hole thoracoscopic radical resection of lung cancer.

Authors:  Yongkai Wu; Min Xu; Yegang Ma
Journal:  J BUON       Date:  2020 Jul-Aug       Impact factor: 2.533

Review 10.  [Minimally Invasive Therapies for Early Stage Non-small Cell Lung Cancer].

Authors:  Tianyu He; Jinlin Cao; Jinming Xu; Wang Lv; Jian Hu
Journal:  Zhongguo Fei Ai Za Zhi       Date:  2020-02-28
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