Literature DB >> 2817865

Inhibition of growth of the dimorphic fungus Paracoccidioides brasiliensis by ajoene.

G San-Blas1, F San-Blas, F Gil, L Mariño, R Apitz-Castro.   

Abstract

Ajoene, a garlic-derived compound that prevents platelet activation, inhibited the growth of Paracoccidioides brasiliensis, a fungal pathogen for humans, by affecting the integrity of the fungal cytoplasmic membrane. This action may be the basis for the study of ajoene as a possible specific antifungal drug.

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Year:  1989        PMID： 2817865      PMCID： PMC172723          DOI： 10.1128/AAC.33.9.1641

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  10 in total

1.  A morphological mutant of Paracoccidioides brasiliensis strain IVIC Pb9. Isolation and wall characterization.

Authors:  F San-Blas; G San-Blas; L J Cova
Journal:  J Gen Microbiol       Date:  1976-04

2.  In vitro susceptibility of Paracoccidioides brasiliensis yeast form to antifungal agents.

Authors:  A Restrepo; C de B Tabares
Journal:  Rev Inst Med Trop Sao Paulo       Date:  1984 Nov-Dec       Impact factor: 1.846

Review 3.  Paracoccidioides brasiliensis: cell wall glucans, pathogenicity, and dimorphism.

Authors:  G San-Blas
Journal:  Curr Top Med Mycol       Date:  1985

4.  Ajoene, the antiplatelet compound derived from garlic, specifically inhibits platelet release reaction by affecting the plasma membrane internal microviscosity.

Authors:  F Rendu; D Daveloose; J C Debouzy; N Bourdeau; S Levy-Toledano; M K Jain; R Apitz-Castro
Journal:  Biochem Pharmacol       Date:  1989-04-15       Impact factor: 5.858

5.  Antifungal activity of ajoene derived from garlic.

Authors:  S Yoshida; S Kasuga; N Hayashi; T Ushiroguchi; H Matsuura; S Nakagawa
Journal:  Appl Environ Microbiol       Date:  1987-03       Impact factor: 4.792

6.  Effects of garlic extract and of three pure components isolated from it on human platelet aggregation, arachidonate metabolism, release reaction and platelet ultrastructure.

Authors:  R Apitz-Castro; S Cabrera; M R Cruz; E Ledezma; M K Jain
Journal:  Thromb Res       Date:  1983-10-15       Impact factor: 3.944

7.  Reversible prevention of platelet activation by (E,Z)-4,5,9-trithiadodeca-1,6,11-triene 9-oxide (ajoene) in dogs under extracorporeal circulation.

Authors:  R Apitz-Castro; E Ledezma; J Escalante; A Jorquera; F M Pinãte; J Moreno-Rea; G Carrillo; O Leal; M K Jain
Journal:  Arzneimittelforschung       Date:  1988-07

8.  In vitro susceptibility testing of Paracoccidioides brasiliensis to sulfonamides.

Authors:  A Restrepo; M D Arango
Journal:  Antimicrob Agents Chemother       Date:  1980-07       Impact factor: 5.191

9.  Effect of detergents on membrane-associated glucan synthetase from Paracoccidioides brasiliensis.

Authors:  G San-Blas; F San-Blas
Journal:  J Bacteriol       Date:  1982-11       Impact factor: 3.490

10.  Ultrastructure of dimorphic transformation in paracoccidioides brasiliensis.

Authors:  L M Carbonell
Journal:  J Bacteriol       Date:  1969-11       Impact factor: 3.490
  10 in total
  10 in total

Review 1.  Plant products as antimicrobial agents.

Authors:  M M Cowan
Journal:  Clin Microbiol Rev       Date:  1999-10       Impact factor: 26.132

2.  Inhibition of microbial growth by ajoene, a sulfur-containing compound derived from garlic.

Authors:  R Naganawa; N Iwata; K Ishikawa; H Fukuda; T Fujino; A Suzuki
Journal:  Appl Environ Microbiol       Date:  1996-11       Impact factor: 4.792

3.  In vivo activity of ajoene against rodent malaria.

Authors:  H A Perez; M De la Rosa; R Apitz
Journal:  Antimicrob Agents Chemother       Date:  1994-02       Impact factor: 5.191

4.  S-Adenosyl-L-methionine inhibitors delta(24)-sterol methyltransferase and delta(24(28))-sterol methylreductase as possible agents against Paracoccidioides brasiliensis.

Authors:  Gonzalo Visbal; Alvaro Alvarez; Belisario Moreno; Gioconda San-Blas
Journal:  Antimicrob Agents Chemother       Date:  2003-09       Impact factor: 5.191

Review 5.  Paracoccidioidomycosis: an update.

Authors:  E Brummer; E Castaneda; A Restrepo
Journal:  Clin Microbiol Rev       Date:  1993-04       Impact factor: 26.132

6.  Investigating the responses of Cronobacter sakazakii to garlic-drived organosulfur compounds: a systematic study of pathogenic-bacterium injury by use of high-throughput whole-transcriptome sequencing and confocal micro-raman spectroscopy.

Authors:  Shaolong Feng; Tyson P Eucker; Mayumi K Holly; Michael E Konkel; Xiaonan Lu; Shuo Wang
Journal:  Appl Environ Microbiol       Date:  2013-11-22       Impact factor: 4.792

Review 7.  Early state research on antifungal natural products.

Authors:  Melyssa Negri; Tânia P Salci; Cristiane S Shinobu-Mesquita; Isis R G Capoci; Terezinha I E Svidzinski; Erika Seki Kioshima
Journal:  Molecules       Date:  2014-03-07       Impact factor: 4.411

8.  Antimicrobial effect of farnesol, a Candida albicans quorum sensing molecule, on Paracoccidioides brasiliensis growth and morphogenesis.

Authors:  Lorena S Derengowski; Calliandra De-Souza-Silva; Shélida V Braz; Thiago M Mello-De-Sousa; Sônia N Báo; Cynthia M Kyaw; Ildinete Silva-Pereira
Journal:  Ann Clin Microbiol Antimicrob       Date:  2009-04-29       Impact factor: 3.944

Review 9.  Paracoccidioides-host Interaction: An Overview on Recent Advances in the Paracoccidioidomycosis.

Authors:  Haroldo C de Oliveira; Patrícia A Assato; Caroline M Marcos; Liliana Scorzoni; Ana C A de Paula E Silva; Julhiany De Fátima Da Silva; Junya de Lacorte Singulani; Kaila M Alarcon; Ana M Fusco-Almeida; Maria J S Mendes-Giannini
Journal:  Front Microbiol       Date:  2015-11-25       Impact factor: 5.640

10.  Antifungal activity of liriodenine on agents of systemic mycoses, with emphasis on the genus Paracoccidioides.

Authors:  Adriele Dandara Levorato Vinche; Iván de-la-Cruz-Chacón; Alma Rosa González-Esquinca; Julhiany de Fátima da Silva; Gisela Ferreira; Daniela Carvalho Dos Santos; Hans Garcia Garces; Daniela Vanessa Moris de Oliveira; Camila Marçon; Ricardo de Souza Cavalcante; Rinaldo Poncio Mendes
Journal:  J Venom Anim Toxins Incl Trop Dis       Date:  2020-10-28
  10 in total

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