| Literature DB >> 28178233 |
David E Jarvis1, Yung Shwen Ho1, Damien J Lightfoot1, Sandra M Schmöckel1, Bo Li1, Theo J A Borm2, Hajime Ohyanagi3, Katsuhiko Mineta4, Craig T Michell5, Noha Saber1, Najeh M Kharbatia6, Ryan R Rupper7, Aaron R Sharp7, Nadine Dally8, Berin A Boughton9, Yong H Woo1, Ge Gao1, Elio G W M Schijlen10, Xiujie Guo1, Afaque A Momin3, Sónia Negrão1, Salim Al-Babili1, Christoph Gehring1, Ute Roessner9, Christian Jung8, Kevin Murphy1, Stefan T Arold3, Takashi Gojobori3, C Gerard van der Linden2, Eibertus N van Loo2, Eric N Jellen7, Peter J Maughan7, Mark Tester1.
Abstract
Chenopodium quinoa (quinoa) is a highly nutritious grain identified as an important crop to improve world food security. Unfortunately, few resources are available to facilitate its genetic improvement. Here we report the assembly of a high-quality, chromosome-scale reference genome sequence for quinoa, which was produced using single-molecule real-time sequencing in combination with optical, chromosome-contact and genetic maps. We also report the sequencing of two diploids from the ancestral gene pools of quinoa, which enables the identification of sub-genomes in quinoa, and reduced-coverage genome sequences for 22 other samples of the allotetraploid goosefoot complex. The genome sequence facilitated the identification of the transcription factor likely to control the production of anti-nutritional triterpenoid saponins found in quinoa seeds, including a mutation that appears to cause alternative splicing and a premature stop codon in sweet quinoa strains. These genomic resources are an important first step towards the genetic improvement of quinoa.Entities:
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Year: 2017 PMID： 28178233 DOI： 10.1038/nature21370
Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962