Literature DB >> 28167564

Multiclonal Expansion of Klebsiella pneumoniae Isolates Producing NDM-1 in Rio de Janeiro, Brazil.

Caio Augusto Martins Aires1, Polyana Silva Pereira1, Carlos Felipe Machado de Araujo1, Thiago Pavoni Gomes Chagas1, Jane Cleide Ribeiro Oliveira2, Sibelle Nogueira Buonora3, Rodolpho Mattos Albano4, Ana Paula D'Alincourt Carvalho-Assef1, Marise Dutra Asensi5.   

Abstract

We characterized NDM-1-producing Klebsiella isolates from Rio de Janeiro, Brazil. PCR was applied for resistance and virulence determinants. The genetic context of blaNDM was determined by S1 nuclease pulsed-field gel electrophoresis (PFGE) and hybridization. Genotyping was performed by PFGE and multilocus sequence typing (MLST). Most isolates carried multiple resistance genes and remained susceptible to amikacin, fosfomycin-trometamol, polymyxin B, and tigecycline. The spread of NDM-1-producing Klebsiella pneumoniae was not associated with clonal expansion and appears to be associated with Tn3000.
Copyright © 2017 American Society for Microbiology.

Entities:  

Keywords:  Klebsiella pneumoniae; MLST; NDM carbapenemase; New Delhi metallo-β-lactamase; molecular typing

Mesh：

Substances：

Year:  2017        PMID： 28167564      PMCID： PMC5365670          DOI： 10.1128/AAC.01048-16

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  36 in total

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Authors:  Polyana Silva Pereira; Carlos Felipe Machado de Araujo; Liliane Miyuki Seki; Viviane Zahner; Ana Paula D'Alincourt Carvalho-Assef; Marise Dutra Asensi
Journal:  J Antimicrob Chemother       Date:  2012-10-15       Impact factor: 5.790

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Journal:  Microb Drug Resist       Date:  2013-06-29       Impact factor: 3.431

5.  Emergence of NDM-1-producing Enterobacteriaceae in Porto Alegre, Brazil.

Authors:  Franciéli P Rozales; Vanessa B Ribeiro; Cibele M Magagnin; Mariana Pagano; Larissa Lutz; Diego R Falci; Adão Machado; Afonso L Barth; Alexandre P Zavascki
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7.  [Resistance to gentamicin, amikacin and ciprofloxacin among nosocomial isolates of klebsiella pneumoniae subspecie pneumoniae producing extended spectrum beta-lactamases].

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10.  Virulent clones of Klebsiella pneumoniae: identification and evolutionary scenario based on genomic and phenotypic characterization.

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Journal:  Front Microbiol       Date:  2018-03-06       Impact factor: 5.640

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Authors:  F Martino; N Tijet; R Melano; A Petroni; E Heinz; D De Belder; D Faccone; M Rapoport; E Biondi; V Rodrigo; M Vazquez; F Pasteran; N R Thomson; A Corso; S A Gomez
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  5 in total

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