Literature DB >> 28160037

Effect of comorbidities on the association between age and hospital mortality after fall-related hip fracture in elderly patients.

A Padrón-Monedero1, T López-Cuadrado2, I Galán2,3, E V Martínez-Sánchez2,4, P Martin5, R Fernández-Cuenca2,4.   

Abstract

The relation between age and mortality after hip fracture was analyzed in elderly patients. 5.5% of the 31,884 patients died. Compared to those 65-74 years old, the multivariate OR for mortality for those 75-84 and ≥85 were 2.11 (95% CI: 1.61-2.77) and 4.10 (95% CI: 3.14-5.35).
PURPOSE: To analyze the impact of Elixhauser comorbidities on the relation between age and mortality after hip fracture in elderly patients.
METHODS: Cross-sectional study of the population ≥65 years old hospitalized in Spain in 2013 with a diagnosis of fall-related hip fracture in the Basic Minimum Set Data (BMSD). The impact of Elixhauser comorbidities on the association between mortality and age groups (65-74, 75-84, ≥85) was analyzed by logistic regression models with progressive adjustment for demographic variables and comorbidities introduced individually.
RESULTS: We identified 31,884 patients, 5.5% of which died during hospitalization. Compared with those 65-74 years old, the multivariate OR of mortality for those 75-84 and ≥85 years old decreased from 2.23 (95% CI: 1.71-2.90) and 4.57 (95% CI: 3.54-5.90) to 2.11 (95% CI: 1.61-2.77) and 4.10 (95% CI: 3.14-5.35), respectively after adjustment for comorbidities. The OR of mortality for men was 1.77 (95% CI: 1.58-1.98) compared to women. The comorbidities with higher OR for mortality were congestive heart failure (OR: 3.88; 95% CI: 3.42-4.41), metastasis (OR: 3.44; 95% CI: 2.27-5.20), fluid and electrolyte disorders (OR: 2.95; 95% CI: 2.47-3.52), coagulation deficiencies (OR: 2.87; 95% CI: 2.08-3.96), and liver disease (OR: 2.40; 95% CI: 1.82-3.17).
CONCLUSIONS: The association between age and mortality after hip fracture remains after adjusting for numerous comorbidities. However, some potentially controllable disorders are associated with an increased risk for mortality, thus, improving their management could benefit survival.

Entities:  

Keywords:  Comorbidities; Elderly; Falls; Mortality

Mesh:

Year:  2017        PMID: 28160037     DOI: 10.1007/s00198-017-3926-2

Source DB:  PubMed          Journal:  Osteoporos Int        ISSN: 0937-941X            Impact factor:   4.507


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Review 10.  Internal fixation versus arthroplasty for displaced femoral neck fractures: what is the evidence?

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  9 in total

1.  Analysis of the Surgical Outcomes in Elderly Patients with Hip Fractures Combined with Hemiplegia.

Authors:  Jinqiang Wang; Hongtao Luo; Qi Wang; Xiaohui Zhu
Journal:  Clin Interv Aging       Date:  2022-07-15       Impact factor: 3.829

2.  Mortality trends for accidental falls in older people in Spain, 2000-2015.

Authors:  Alicia Padrón-Monedero; Javier Damián; M Pilar Martin; Rafael Fernández-Cuenca
Journal:  BMC Geriatr       Date:  2017-11-28       Impact factor: 3.921

3.  Liver disease and mortality among patients with hip fracture: a population-based cohort study.

Authors:  Jonathan Montomoli; Rune Erichsen; Henrik Gammelager; Alma B Pedersen
Journal:  Clin Epidemiol       Date:  2018-08-21       Impact factor: 4.790

4.  The use of Barthel index for the assessment of the functional recovery after osteoporotic hip fracture: One year follow-up.

Authors:  Ana P Mayoral; Elena Ibarz; Luis Gracia; Jesús Mateo; Antonio Herrera
Journal:  PLoS One       Date:  2019-02-07       Impact factor: 3.240

5.  Elderly patients with concurrent hip fracture and lower respiratory tract infection: the pathogens and prognosis over different bedridden periods.

Authors:  Yuan Yuan; Wei Tian; Xiaohui Deng; Rui Yue; Xiaozhu Ge; Xinbao Wu; Ping Zhang
Journal:  J Orthop Surg Res       Date:  2021-04-13       Impact factor: 2.359

6.  Chronic liver disease and cirrhosis increase morbidity in geriatric patients treated surgically for hip fractures: analysis of the US Nationwide Inpatient Sample.

Authors:  Feng-Jen Tseng; Guo-Hau Gou; Sheng-Hao Wang; Jia-Fwu Shyu; Ru-Yu Pan
Journal:  BMC Geriatr       Date:  2022-02-23       Impact factor: 3.921

7.  Refracture and mortality following hospitalization for severe osteoporotic fractures: The Fractos Study.

Authors:  Christian Roux; Thierry Thomas; Julien Paccou; Geoffray Bizouard; Anne Crochard; Emese Toth; Magali Lemaitre; Frédérique Maurel; Laure Perrin; Florence Tubach
Journal:  JBMR Plus       Date:  2021-05-14

8.  Mortality Risk Assessment at the Admission in Patient With Proximal Femur Fractures: Electrolytes and Renal Function.

Authors:  Giulio Edoardo Vigni; Francesco Bosco; Alessio Cioffi; Lawrence Camarda
Journal:  Geriatr Orthop Surg Rehabil       Date:  2021-02-09

9.  [Risk factors affecting mortality in patients with hip fractures at a regional trauma center].

Authors:  Ali Darwich; Elio Assaf; Roman Klein; Sascha Gravius; Christoph G Wölfl; Ahmed Jawhar
Journal:  Z Gerontol Geriatr       Date:  2021-03-23       Impact factor: 1.281

  9 in total

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