Literature DB >> 28159405

[Immune system and tumors].

Magali Terme1, Corinne Tanchot2.   

Abstract

Despite having been much debated, it is now well established that the immune system plays an essential role in the fight against cancer. In this article, we will highlight the implication of the immune system in the control of tumor growth and describe the major components of the immune system involved in the antitumoral immune response. The immune system, while exerting pressure on tumor cells, also will play a pro-tumoral role by sculpting the immunogenicity of tumors cells as they develop. Finally, we will illustrate the numerous mechanisms of immune suppression that take place within the tumoral microenvironment which allow tumor cells to escape control from the immune system. The increasingly precise knowledge of the brakes to an effective antitumor immune response allows the development of immunotherapy strategies more and more innovating and promising of hope.
Copyright © 2016. Published by Elsevier Masson SAS.

Entities:  

Keywords:  Cancer; Escape; Immune suppression; Immune surveillance; Immunologie; Immunology; Immunosuppression; Immunosurveillance; Échappement

Mesh:

Substances:

Year:  2017        PMID: 28159405     DOI: 10.1016/j.annpat.2016.12.004

Source DB:  PubMed          Journal:  Ann Pathol        ISSN: 0242-6498            Impact factor:   0.407


  3 in total

1.  TLR4 promoter rs1927914 variant contributes to the susceptibility of esophageal squamous cell carcinoma in the Chinese population.

Authors:  Jiaying Li; Hongjiao Wu; Hui Gao; Ruihuan Kou; Yuning Xie; Zhi Zhang; Xuemei Zhang
Journal:  PeerJ       Date:  2021-02-01       Impact factor: 2.984

2.  A Prognostic Signature Based on Immunogenomic Profiling Offers Guidance for Esophageal Squamous Cell Cancer Treatment.

Authors:  Jianyao Gao; Ting Tang; Baohui Zhang; Guang Li
Journal:  Front Oncol       Date:  2021-02-24       Impact factor: 6.244

3.  Impact of Bone Marrow miR-21 Expression on Acute Myeloid Leukemia T Lymphocyte Fragility and Dysfunction.

Authors:  Douâa Moussa Agha; Redouane Rouas; Mehdi Najar; Fatima Bouhtit; Hussein Fayyad-Kazan; Laurence Lagneaux; Dominique Bron; Nathalie Meuleman; Philippe Lewalle; Makram Merimi
Journal:  Cells       Date:  2020-09-08       Impact factor: 6.600

  3 in total

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