| Literature DB >> 28157502 |
Abstract
Adaptation of CRISPR-Cas9 for genome-editing applications has revolutionized biomedical research. New single-component effector CRISPR systems are emerging from the bioinformatics pipeline. How can we best harness their power? Three new studies will no doubt facilitate this transition by generating the C2c1 and C2c2 structure snapshots in different functional states.Keywords: C2c1; C2c2; C2c3; CRISPR; Cas; Cas9; Cpf1; immunity; interference; type II
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Year: 2017 PMID： 28157502 DOI： 10.1016/j.molcel.2017.01.024
Source DB: PubMed Journal: Mol Cell ISSN： 1097-2765 Impact factor: 17.970