| Literature DB >> 28150243 |
Rudolf T Pillich1, Jing Chen2, Vladimir Rynkov2, David Welker2, Dexter Pratt2.
Abstract
Networks are a powerful and flexible paradigm that facilitate communication and computation about interactions of any type, whether social, economic, or biological. NDEx, the Network Data Exchange, is an online commons to enable new modes of collaboration and publication using biological networks. NDEx creates an access point and interface to a broad range of networks, whether they express molecular interactions, curated relationships from literature, or the outputs of systematic analysis of big data. Research organizations can use NDEx as a distribution channel for networks they generate or curate. Developers of bioinformatic applications can store and query NDEx networks via a common programmatic interface. NDEx can also facilitate the integration of networks as data in electronic publications, thus making a step toward an ecosystem in which networks bearing data, hypotheses, and findings flow seamlessly between scientists.Keywords: Big data; BioPAX3; Biological networks; Cyberinfrastructure; Cytoscape; Java; Open source; OpenBEL; Pathway analysis; Provenance; Python; REST API
Mesh:
Year: 2017 PMID: 28150243 DOI: 10.1007/978-1-4939-6783-4_13
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745