Literature DB >> 28149897

Idolizing the clearance of Amyloid-β by microglia.

Nienke Marlies Van Loon1, Noam Zelcer1.   

Abstract

Entities:  

Year:  2016        PMID： 28149897      PMCID： PMC5233474          DOI： 10.21037/atm.2016.11.63

Source DB:  PubMed          Journal:  Ann Transl Med        ISSN： 2305-5839


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  20 in total

1.  Reelin protects against amyloid β toxicity in vivo.

Authors:  Courtney Lane-Donovan; Gary T Philips; Catherine R Wasser; Murat S Durakoglugil; Irene Masiulis; Ajeet Upadhaya; Theresa Pohlkamp; Cagil Coskun; Tiina Kotti; Laura Steller; Robert E Hammer; Michael Frotscher; Hans H Bock; Joachim Herz
Journal:  Sci Signal       Date:  2015-07-07       Impact factor: 8.192

2.  The E3 ubiquitin ligase IDOL induces the degradation of the low density lipoprotein receptor family members VLDLR and ApoER2.

Authors:  Cynthia Hong; Sarah Duit; Pilvi Jalonen; Ruud Out; Lilith Scheer; Vincenzo Sorrentino; Rima Boyadjian; Kees W Rodenburg; Edan Foley; Laura Korhonen; Dan Lindholm; Johannes Nimpf; Theo J C van Berkel; Peter Tontonoz; Noam Zelcer
Journal:  J Biol Chem       Date:  2010-04-28       Impact factor: 5.157

3.  Targeted disruption of the idol gene alters cellular regulation of the low-density lipoprotein receptor by sterols and liver x receptor agonists.

Authors:  Elena Scotti; Cynthia Hong; Yuko Yoshinaga; Yiping Tu; Yan Hu; Noam Zelcer; Rima Boyadjian; Pieter J de Jong; Stephen G Young; Loren G Fong; Peter Tontonoz
Journal:  Mol Cell Biol       Date:  2011-02-22       Impact factor: 4.272

4.  Identification of a loss-of-function inducible degrader of the low-density lipoprotein receptor variant in individuals with low circulating low-density lipoprotein.

Authors:  Vincenzo Sorrentino; Sigrid W Fouchier; Mohammad M Motazacker; Jessica K Nelson; Joep C Defesche; Geesje M Dallinga-Thie; John J P Kastelein; G Kees Hovingh; Noam Zelcer
Journal:  Eur Heart J       Date:  2013-01-16       Impact factor: 29.983

Review 5.  ApoE and Aβ in Alzheimer's disease: accidental encounters or partners?

Authors:  Takahisa Kanekiyo; Huaxi Xu; Guojun Bu
Journal:  Neuron       Date:  2014-02-19       Impact factor: 17.173

6.  Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance.

Authors:  Jungsu Kim; Joseph M Castellano; Hong Jiang; Jacob M Basak; Maia Parsadanian; Vi Pham; Stephanie M Mason; Steven M Paul; David M Holtzman
Journal:  Neuron       Date:  2009-12-10       Impact factor: 17.173

7.  Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood Aβ clearance in a mouse model of β-amyloidosis.

Authors:  Joseph M Castellano; Rashid Deane; Andrew J Gottesdiener; Philip B Verghese; Floy R Stewart; Tim West; Andrew C Paoletti; Tristan R Kasper; Ronald B DeMattos; Berislav V Zlokovic; David M Holtzman
Journal:  Proc Natl Acad Sci U S A       Date:  2012-08-27       Impact factor: 11.205

Review 8.  LXR Regulation of Brain Cholesterol: From Development to Disease.

Authors:  Rebecca Courtney; Gary E Landreth
Journal:  Trends Endocrinol Metab       Date:  2016-04-21       Impact factor: 12.015

9.  LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor.

Authors:  Noam Zelcer; Cynthia Hong; Rima Boyadjian; Peter Tontonoz
Journal:  Science       Date:  2009-06-11       Impact factor: 47.728

10.  Improvement of memory deficits and amyloid-β clearance in aged APP23 mice treated with a combination of anti-amyloid-β antibody and LXR agonist.

Authors:  Nicholas F Fitz; Emilie L Castranio; Alexis Y Carter; Ravindra Kodali; Iliya Lefterov; Radosveta Koldamova
Journal:  J Alzheimers Dis       Date:  2014       Impact factor: 4.472
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  2 in total

1.  Morphological and functional changes of microglia cultured under different oxygen concentrations and the analysis of related mechanisms.

Authors:  Xing Wu; Tengbo Yu; Hongyan Xu; Xiuming Sun; Dewei Kou; Liping Li
Journal:  Exp Ther Med       Date:  2017-12-05       Impact factor: 2.447

2.  Structural analysis of the LDL receptor-interacting FERM domain in the E3 ubiquitin ligase IDOL reveals an obscured substrate-binding site.

Authors:  Luca Martinelli; Athanassios Adamopoulos; Patrik Johansson; Paul T Wan; Jenny Gunnarsson; Hongwei Guo; Helen Boyd; Noam Zelcer; Titia K Sixma
Journal:  J Biol Chem       Date:  2020-07-29       Impact factor: 5.157
  2 in total

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